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使用分类法系统地识别和描述 COPD 随机试验中的自我管理干预措施成分。

Using a Taxonomy to Systematically Identify and Describe Self-Management Interventions Components in Randomized Trials for COPD.

机构信息

Netherlands Institute for Health Services Research (NIVEL), 3513 Utrecht, The Netherlands.

Avedis Donabedian Research Institute (FAD), 08037 Barcelona, Spain.

出版信息

Int J Environ Res Public Health. 2022 Oct 4;19(19):12685. doi: 10.3390/ijerph191912685.

Abstract

Self-management interventions (SMIs) may improve outcomes in Chronic Obstructive Pulmonary Disease (COPD). However, accurate comparisons of their relative effectiveness are challenging, partly due to a lack of clarity and detail regarding the intervention content being evaluated. This study systematically describes intervention components and characteristics in randomized controlled trials (RCTs) related to COPD self-management using the COMPAR-EU taxonomy as a framework, identifying components that are insufficiently incorporated into the design of the intervention or insufficiently reported. Overall, 235 RCTs published between 2010 and 2018, from a systematic review were coded using the taxonomy, which includes 132 components across four domains: intervention characteristics, expected patient (or caregiver) self-management behaviours, patient relevant outcomes, and target population characteristics. Risk of bias was also assessed. Interventions mainly focused on physical activity (67.4%), and condition-specific behaviours like breathing exercise (63.5%), self-monitoring (50.8%), and medication use (33.9%). Support techniques like education and skills-training, self-monitoring, and goal setting (over 35% of the RCTs) were mostly used for this. Emotional-based techniques, problem-solving, and shared decision-making were less frequently reported (less than 15% of the studies). Numerous SMIs components were insufficiently incorporated into the design of COPD SMIs or insufficiently reported. Characteristics like mode of delivery, intensity, location, and providers involved were often not described. Only 8% of the interventions were tailored to the target population's characteristics. Outcomes that are considered important by patients were hardly taken into account. There is still a lot to improve in both the design and description of SMIs for COPD. Using a framework such as the COMPAR-EU SMI taxonomy may contribute to better reporting and to better informing of replication efforts. In addition, prospective use of the taxonomy for developing and reporting intervention content would further aid in building a cumulative science of effective SMIs in COPD.

摘要

自我管理干预(SMI)可能改善慢性阻塞性肺疾病(COPD)的结局。然而,由于缺乏对所评估干预内容的明确性和详细信息,准确比较其相对有效性具有挑战性。本研究使用 COMPAR-EU 分类法系统地描述了与 COPD 自我管理相关的随机对照试验(RCT)中的干预组成部分和特征,确定了干预设计中未充分纳入或报告不足的组成部分。总体而言,2010 年至 2018 年,一项系统综述中发表的 235 项 RCT 使用该分类法进行了编码,该分类法包括四个领域的 132 个组成部分:干预特征、预期患者(或照顾者)自我管理行为、患者相关结局和目标人群特征。还评估了偏倚风险。干预措施主要集中在身体活动(67.4%)和特定于疾病的行为,如呼吸练习(63.5%)、自我监测(50.8%)和药物使用(33.9%)。支持技术,如教育和技能培训、自我监测和目标设定(超过 35%的 RCT)主要用于此目的。情绪为基础的技术、解决问题和共同决策的报告较少(不到 15%的研究)。许多 SMI 组成部分未充分纳入 COPD SMI 的设计或报告不足。诸如交付模式、强度、地点和涉及的提供者等特征通常未被描述。只有 8%的干预措施针对目标人群的特征进行了调整。患者认为重要的结局几乎没有被考虑到。在 COPD 的 SMI 的设计和描述方面仍有很多需要改进的地方。使用 COMPAR-EU SMI 分类法等框架可能有助于更好地报告和更好地为复制工作提供信息。此外,前瞻性使用该分类法开发和报告干预内容将进一步有助于建立 COPD 有效 SMI 的累积科学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da86/9566761/499aa675cd88/ijerph-19-12685-g001.jpg

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