Zulkiflee Izzat, Masri Syafira, Zawani Mazlan, Salleh Atiqah, Amirrah Ibrahim Nor, Wee Mohd Farhanulhakim Mohd Razip, Yusop Salma Mohamad, Fauzi Mh Busra
Centre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaakob Latiff, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Institute of Microengineering and Nanoelectrics, Universiti Kebangsaan Malaysia, Bangi 43600, Malaysia.
Polymers (Basel). 2022 Oct 8;14(19):4219. doi: 10.3390/polym14194219.
Silicon has made its breakthrough in various industries, including clinical and biomedical applications. Silicon-based biomaterials that were fabricated into various types of scaffolds may attract interest due to their highly favorable properties covering their excellent biocompatibility, high surface area, mechanical strength, and selectivity depending on their application including film, hydrogel, nanoparticles, and so on. Silicon-based materials have also shown exciting results involving cell culture, cell growth, as well as tissue engineering. In this article, a simple review compromising the evaluation of silicon's unique properties has been discussed and followed by the application of the silicone-based product in future perspectives in biomedical fields. The review goals are to widen and inspire broader interest in silicone-based materials in wound healing research.
硅已在包括临床和生物医学应用在内的各个行业取得突破。制成各种类型支架的硅基生物材料可能因其具有高度良好的特性而受到关注,这些特性包括出色的生物相容性、高表面积、机械强度以及根据其应用(包括薄膜、水凝胶、纳米颗粒等)的选择性。硅基材料在细胞培养、细胞生长以及组织工程方面也显示出令人兴奋的结果。在本文中,对硅独特性能评估的简单综述进行了讨论,随后探讨了硅基产品在生物医学领域未来的应用前景。综述的目的是拓宽并激发对硅基材料在伤口愈合研究方面更广泛的兴趣。