Shanmukham Bhaskaran, Varman Mahendra, Subbarayan Sarojini, Sakthivadivel Varatharajan, Kaliappan Ariyanachi, Gaur Archana, Jyothi Lakshmi
General Medicine, Melamruvathur Adhiparasakthi Institute of Medical Sciences and Research, Melmaruvathur, IND.
Pediatrics, Sri Muthukumaran Medical College Hospital and Research Institute, Chennai, IND.
Cureus. 2022 Sep 12;14(9):e29077. doi: 10.7759/cureus.29077. eCollection 2022 Sep.
Introduction End-stage renal disease (ESRD) has increased in India due to the growing load of non-communicable diseases. The most prevalent psychological issue among these patients has been identified as depression, which may have an impact on treatment success. Around 20% to 90% of hemodialysis patients experience depression. The current study aimed to determine the prevalence of depression among patients undergoing hemodialysis as well as the relationship between this condition and the sociodemographic and clinical parameters of the patients. Methods Basic demographic information and particulars of chronic morbidity, duration, and the number of cycles of hemodialysis per week were noted. The Beck Depression Inventory (BDI) score was administered to screen for depression. Results A total of 92 participants were enrolled in the study; 69 (75%) were males. The mean age of participants was 52 years. Hypertension (100%) was the most common co-morbidity followed by diabetes mellitus (38%). The mean duration of chronic kidney disease was 3.9 years. The majority (68.5%) had hemodialysis twice per week. Forty-one percent (41%) screened positive for borderline clinical depression or more. The mean BDI score was 17.07. The number of hemodialyses per week had a significant relation with depression with an odds ratio of 4.16 and 95% CI of 1.4-12.38. Conclusion Depression is prevalent among patients with chronic kidney disease who are on dialysis. The management of this preventable illness demands a repertoire of measures such as launching a program for the detection and treatment of depression combining psychiatric professionals and social volunteer organizations.
引言 由于非传染性疾病负担的增加，印度的终末期肾病（ESRD）有所增加。这些患者中最普遍的心理问题已被确定为抑郁症，这可能会影响治疗效果。大约20%至90%的血液透析患者患有抑郁症。本研究旨在确定接受血液透析患者中抑郁症的患病率，以及这种情况与患者社会人口统计学和临床参数之间的关系。方法 记录基本人口统计学信息以及慢性疾病、病程和每周血液透析次数的详细情况。采用贝克抑郁量表（BDI）评分来筛查抑郁症。结果 共有92名参与者纳入研究；69名（75%）为男性。参与者的平均年龄为52岁。高血压（100%）是最常见的合并症，其次是糖尿病（38%）。慢性肾病的平均病程为3.9年。大多数（68.5%）患者每周进行两次血液透析。41%的患者筛查出临界临床抑郁症或更严重的抑郁症呈阳性。BDI平均评分为17.07。每周血液透析次数与抑郁症有显著关系，比值比为4.16，95%置信区间为1.4 - 12.38。结论 抑郁症在接受透析的慢性肾病患者中普遍存在。对这种可预防疾病的管理需要一系列措施，例如启动一个结合精神科专业人员和社会志愿者组织的抑郁症检测与治疗项目。
