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大鼠胃肠道pH值测量:微生物菌群、饮食和禁食的影响。

Gastrointestinal pH measurement in rats: influence of the microbial flora, diet and fasting.

作者信息

Ward F W, Coates M E

出版信息

Lab Anim. 1987 Jul;21(3):216-22. doi: 10.1258/002367787781268693.

DOI:10.1258/002367787781268693
PMID:3626468
Abstract

The pH of the rat intestinal tract was decreased by the presence of a microbial flora, but its influence in the forestomach is less clear. Stomach pH values varied according to the amount of food present at the time of measurement. Fasting increased the pH of the gastrointestinal tract in conventional rats but had little effect in germfree rats. In the conventional rat, feeding a purified diet compared with a commercial diet resulted in a lower pH in the forestomach and a higher pH in the caecal contents. Magnesium trisilicate promoted gastric emptying in conventional rats and its antacid effect was observed only in the caecum and colon.

摘要

微生物菌群的存在会降低大鼠肠道的pH值,但其对前胃的影响尚不清楚。胃的pH值会根据测量时食物的量而变化。禁食会使常规饲养大鼠的胃肠道pH值升高,但对无菌大鼠影响不大。在常规饲养的大鼠中,与喂食商业饲料相比,喂食纯化饲料会导致前胃pH值降低,盲肠内容物pH值升高。三硅酸镁促进常规饲养大鼠的胃排空,并且仅在盲肠和结肠中观察到其抗酸作用。

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