FTO与人体测量学：可改变因素的作用。
FTO and Anthropometrics: The Role of Modifiable Factors.
作者信息
Evans Cassandra, Curtis Jason, Antonio Jose
机构信息
Health and Human Performance, Nova Southeastern University, Davie, FL 33314, USA.
Healthy Sciences, Rocky Mountain University of Health Professions, Provo, UT 84606, USA.
出版信息
J Funct Morphol Kinesiol. 2022 Oct 18;7(4):90. doi: 10.3390/jfmk7040090.
Abstract
Numerous gene variants are linked to an individual's propensity to become overweight or obese. The most commonly studied gene variant is the FTO single nucleotide polymorphism. The FTO risk allele is linked with increased body mass, BMI and other lifestyle factors that may perpetuate an individual's risk for obesity. Studies assessing eating behaviors, eating preferences, nutrition interventions and other lifestyle factors were reviewed. These studies demonstrated a clear difference in eating behaviors and preferences. Lifestyle modifications including physical activity and diet were effective in weight management even in those with the risk allele.
摘要
许多基因变异与个体超重或肥胖的倾向有关。研究最广泛的基因变异是FTO单核苷酸多态性。FTO风险等位基因与体重增加、体重指数（BMI）以及其他可能使个体肥胖风险持续存在的生活方式因素有关。对评估饮食行为、饮食偏好、营养干预及其他生活方式因素的研究进行了综述。这些研究表明饮食行为和偏好存在明显差异。包括体育活动和饮食在内的生活方式改变对体重管理有效，即使是携带风险等位基因的个体。
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