Suppr超能文献

水提取物的抗菌活性及其对吞噬作用的影响。

Antibacterial Activity of Aqueous Extract and Its Effect on Phagocytosis .

机构信息

General Directorate of Education in Karbala, Karbala, Iraq.

College of Nursing, University of Warith Al-anbiyaa, Karbala, Iraq.

出版信息

Arch Razi Inst. 2022 Apr 30;77(2):545-552. doi: 10.22092/ARI.2022.356956.1946. eCollection 2022 Apr.

Abstract

has been traditionally used for the treatment of several inflammatory diseases, and bacterial resistance to antibiotics has recently increased the use of bioproducts. The present study aimed to assess the antibacterial effect and phagocytic ability of the aqueous extract of the in bacteria isolated in nosocomial infections. plant was collected and prepared from the aqueous extract in different concentrations. A total of 125 samples were collected from various clinical sources, including urine, sputum, wounds, otitis, and blood, from patients of both genders in different age groups. The results demonstrated that out of the 59 infected samples, urine samples had the highest infection (68%), followed by wounds, sputum, and otitis reported as (60%), (44%), and (40%), respectively. On the other hand, blood samples had the lowest percentage of infection (28%). Microscopic diagnostic results, biochemical tests, API Staph System, API 20E System, and Vitek 2 Compact pointed out that the highest infection rates were related to (32.20%), (25.33%), and (22.03%), while the lowest infection rate was detected in (20.33%). The results indicated that aqueous extract of had an antibacterial activity for all bacterial isolates, 25 mg/ml of extract gave an inhibition zone of 10.8 mm,10.4 mm, 7mm, and 10mm for , , , and , respectively, while 200 mg/ml of extract gave 24 mm, 22 mm, 18.4 mm, and 20 mm, respectively. The results pointed to a significant increase in the phagocytosis rate, with the phagocytosis of blood samples treated with extract (79.7%), as compared to control samples (57.75%). As evidenced by the results of this study, the aqueous extract of the plant showed antibacterial effects and a positive impact on the phagocytic ratio; nonetheless, it is recommended that further studies be conducted to characterize the compounds of this herb.

摘要

该植物已被传统用于治疗多种炎症性疾病,而细菌对抗生素的耐药性最近增加了对生物制品的使用。本研究旨在评估 在医院感染分离菌中的抗菌作用和吞噬能力。从不同的临床来源(包括尿液、痰、伤口、耳炎和血液)共收集了 125 个样本,这些样本来自不同年龄组的男女患者。结果表明,在 59 个感染样本中,尿液样本的感染率最高(68%),其次是伤口、痰和耳炎,分别为(60%)、(44%)和(40%)。另一方面,血液样本的感染率最低(28%)。显微镜诊断结果、生化试验、API Staph 系统、API 20E 系统和 Vitek 2 Compact 指出,感染率最高与 (32.20%)、 (25.33%)和 (22.03%)有关,而感染率最低的是 (20.33%)。结果表明, 的水提物对所有细菌分离株均具有抗菌活性,25mg/ml 的提取物对 、 、 、 的抑制圈分别为 10.8mm、10.4mm、7mm 和 10mm,而 200mg/ml 的提取物的抑制圈分别为 24mm、22mm、18.4mm 和 20mm。结果表明,吞噬率显著增加,用 提取物处理的血液样本的吞噬率(79.7%)高于对照样本(57.75%)。本研究结果表明, 植物的水提物具有抗菌作用,并对吞噬率有积极影响;然而,建议进一步研究以表征该草药的化合物。

相似文献

1
Antibacterial Activity of Aqueous Extract and Its Effect on Phagocytosis .水提取物的抗菌活性及其对吞噬作用的影响。
Arch Razi Inst. 2022 Apr 30;77(2):545-552. doi: 10.22092/ARI.2022.356956.1946. eCollection 2022 Apr.

本文引用的文献

3
Therapeutic potential of boswellic acids: a patent review (1990-2015).乳香酸的治疗潜力:专利综述(1990 - 2015年)
Expert Opin Ther Pat. 2017 Jan;27(1):81-90. doi: 10.1080/13543776.2017.1235156. Epub 2016 Sep 20.
4
Drug resistance in eukaryotic microorganisms.真核微生物的耐药性。
Nat Microbiol. 2016 Jun 24;1(7):16092. doi: 10.1038/nmicrobiol.2016.92.
9
Pseudomonas exotoxin A: from virulence factor to anti-cancer agent.铜绿假单胞菌外毒素A:从致病因子到抗癌药物。
Int J Med Microbiol. 2009 Mar;299(3):161-76. doi: 10.1016/j.ijmm.2008.08.003. Epub 2008 Oct 23.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验