Department of Geriatrics, Hanoi Medical University, Hanoi 100000, Vietnam.
Scientific Research Department, National Geriatric Hospital, Hanoi 100000, Vietnam.
Int J Environ Res Public Health. 2022 Oct 20;19(20):13593. doi: 10.3390/ijerph192013593.
This study aimed to assess the symptom burden among older patients hospitalised for heart failure. This hospital-based, cross-sectional study was conducted at the National Geriatric Hospital, Hanoi, Vietnam, from June 2019 to August 2020. Face-to-face interviews were performed to gather the following information: socio-demographic characteristics, heart failure classification, and clinical characteristics (comorbidities, polypharmacy, pro-B-type natriuretic peptide, left ventricular ejection fraction (LVEF), symptom burden, and depression). Symptom burden was assessed using the Edmonton Symptom Assessment Scale (ESAS), and depression was measured using the Patient Health Questionnaire. A total of 314 patients participated in the study. The mean participant age was 72.67 (SD = 9.42) years. The most frequently reported symptoms on the ESAS were shortness of breath (95.5%), fatigue (94.8%), and anxiety (81.2%). In univariate analyses, depression was significantly associated with heart failure class ( < 0.05). Multivariate linear regression revealed that major depression was significantly associated with total symptom burden score (Beta: 11.74; 95% CI: 9.24-14.23) and LVEF (Beta: -0.09; 95% CI: -0.17-(-0.007)). Patients hospitalised for heart failure experienced a high burden of symptoms. Further studies addressing adverse outcomes and expanding to community-dwelling older people are essential. Palliative care approaches that target symptom reduction should be considered in patients with heart failure.
本研究旨在评估因心力衰竭住院的老年患者的症状负担。这项基于医院的横断面研究于 2019 年 6 月至 2020 年 8 月在越南河内的国家老年医院进行。通过面对面访谈收集以下信息：社会人口统计学特征、心力衰竭分类和临床特征（合并症、多药治疗、脑利钠肽前体、左心室射血分数（LVEF）、症状负担和抑郁）。使用埃德蒙顿症状评估量表（ESAS）评估症状负担，使用患者健康问卷评估抑郁。共有 314 名患者参与了这项研究。参与者的平均年龄为 72.67 岁（标准差=9.42 岁）。ESAS 上报告最多的症状是呼吸困难（95.5%）、疲劳（94.8%）和焦虑（81.2%）。在单因素分析中，抑郁与心力衰竭分级显著相关（<0.05）。多元线性回归显示，重度抑郁症与总症状负担评分（β：11.74；95%置信区间：9.24-14.23）和 LVEF（β：-0.09；95%置信区间：-0.17-(-0.007)）显著相关。因心力衰竭住院的患者经历了高症状负担。进一步研究关注不良结局并扩展到社区居住的老年人是必要的。应该考虑针对心力衰竭患者的症状减轻的姑息治疗方法。
