表面增强拉曼光谱在真菌、细菌和病毒检测中的应用。
Application of SERS in the Detection of Fungi, Bacteria and Viruses.
作者信息
Xia Jiarui, Li Wenwen, Sun Mengtao, Wang Huiting
机构信息
Institute of Health Sciences, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, China Medical University, Shenyang 110001, China.
School of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, China.
出版信息
Nanomaterials (Basel). 2022 Oct 12;12(20):3572. doi: 10.3390/nano12203572.
In this review, we report the recent advances of SERS in fungi, bacteria, and viruses. Firstly, we briefly introduce the advantage of SERS over fluorescence on virus identification and detection. Secondly, we review the feasibility analysis of Raman/SERS spectrum analysis, identification, and fungal detection on SERS substrates of various nanostructures with a signal amplification mechanism. Thirdly, we focus on SERS spectra for nucleic acid, pathogens for the detection of viruses and bacteria, and furthermore introduce SERS-based microdevices, including SERS-based microfluidic devices, and three-dimensional nanostructured plasmonic substrates.
在本综述中，我们报告了表面增强拉曼光谱（SERS）在真菌、细菌和病毒方面的最新进展。首先，我们简要介绍了SERS在病毒识别和检测方面相对于荧光的优势。其次，我们综述了利用具有信号放大机制的各种纳米结构SERS基底进行拉曼/SERS光谱分析、识别和真菌检测的可行性分析。第三，我们重点关注用于核酸、病毒和细菌检测病原体的SERS光谱，此外还介绍了基于SERS的微器件，包括基于SERS的微流控器件和三维纳米结构等离子体基底。
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