Sharmanov T Sh, Kurmangalinov S M, Abishev B Kh, Aĭdarkhanov B B
Vopr Pitan. 1987 May-Jun(3):39-41.
The authors studied the influence of the diet enriched with phosphatidylcholine on the structural-functional parameters of microsomes: lipid peroxidation activity, the levels of cytochromes b5 and P-450, microviscosity of the lipid phase of the membrane. In experiments in vivo it was found that phosphatidylcholine per se, not combined with antioxidants, did not show antioxidant properties. Biological effects of lecithin could be explained by its role as a catalyst of the monooxygenase system in the liver, based on the correlation (r = +0.8) between the high level of cytochrome b5 and the degree of eximerization of the fluorescent probe pyrene in the microsomes.
脂质过氧化活性、细胞色素b5和P - 450水平、膜脂质相的微粘度。在体内实验中发现，磷脂酰胆碱本身，未与抗氧化剂结合时，不显示抗氧化特性。基于微粒体中细胞色素b5的高水平与荧光探针芘的准分子形成程度之间的相关性（r = +0.8），卵磷脂的生物学效应可以用其作为肝脏中单加氧酶系统催化剂的作用来解释。
