Division of Biotechnology, The Catholic University of Korea, Bucheon 14662, Republic of Korea.
J Microbiol Biotechnol. 2022 Nov 28;32(11):1357-1372. doi: 10.4014/jmb.2209.09012. Epub 2022 Oct 21.
Heavy reliance on fossil fuels has been associated with increased climate disasters. As an alternative, microalgae have been proposed as an effective agent for biomass production. Several advantages of microalgae include faster growth, usage of non-arable land, recovery of nutrients from wastewater, efficient CO capture, and high amount of biomolecules that are valuable for humans. Microalgae spp. are a large group of eukaryotic, photosynthetic, unicellular microorganisms with high adaptability to environmental variations. Over the past decades, has been used for the large-scale production of biomass. In addition, has been actively used in various food industries for improving human health because of its antioxidant, antidiabetic, and immunomodulatory functions. However, the major restrictions in microalgal biofuel technology are the cost-consuming cultivation, processing, and lipid extraction processes. Therefore, various trials have been performed to enhance the biomass productivity and the lipid contents of cells. This study provides a comprehensive review of lipid enhancement strategies mainly published in the last five years and aimed at regulating carbon sources, nutrients, stresses, and expression of exogenous genes to improve biomass production and lipid synthesis.
对化石燃料的严重依赖与气候灾害的增加有关。作为替代方案，微藻已被提议作为生物量生产的有效剂。微藻的几个优点包括生长速度更快、可利用非耕地、从废水中回收营养物质、高效 CO 捕获以及含有大量对人类有价值的生物分子。微藻 spp. 是一大组真核、光合、单细胞微生物，对环境变化具有高度适应性。在过去的几十年中，已被用于大规模生产生物质。此外，由于其抗氧化、抗糖尿病和免疫调节功能，已在各种食品工业中积极用于改善人类健康。然而，微藻生物燃料技术的主要限制在于耗费成本的培养、加工和脂质提取过程。因此，已经进行了各种试验来提高微藻细胞的生物量生产力和脂质含量。本研究综述了主要在过去五年内发表的脂质增强策略，旨在调节碳源、营养物、应激和外源基因的表达，以提高生物量生产和脂质合成。
