Ke Gaofeng, Zhang Jia, Gao Wufeng, Chen Jiayi, Liu Luotong, Wang Simiao, Zhang Huan, Yan Guojun
Department of Rehabilitation Medicine, The Affiliated Wenling Hospital of Wenzhou Medical University, Wenling, China.
School of Pharmacy, Jiangsu Provincial Engineering Research Center of Traditional Chinese Medicine External Medication Development and Application, Nanjing University of Chinese Medicine, Nanjing, China.
Front Pharmacol. 2022 Oct 13;13:1038063. doi: 10.3389/fphar.2022.1038063. eCollection 2022.
Although cancer has seriously threatened people's health, it is also identified by the World Health Organization as a controllable, treatable and even curable chronic disease. Traditional Chinese medicine (TCM) has been extensively used to treat cancer due to its multiple targets, minimum side effects and potent therapeutic effects, and thus plays an important role in all stages of tumor therapy. With the continuous progress in cancer treatment, the overall efficacy of cancer therapy has been significantly improved, and the survival time of patients has been dramatically prolonged. In recent years, a series of advanced technologies, including nanotechnology, gene editing technology, real-time cell-based assay (RTCA) technology, and flow cytometry analysis technology, have been developed and applied to study TCM for cancer therapy, which efficiently improve the medicinal value of TCM and accelerate the research progress of TCM in cancer therapy. Therefore, the applications of these advanced technologies in TCM for cancer therapy are summarized in this review. We hope this review will provide a good guidance for TCM in cancer therapy.
尽管癌症已严重威胁人们的健康，但它也被世界卫生组织认定为一种可控、可治甚至可愈的慢性病。由于中药具有多靶点、副作用小、疗效显著等特点，已被广泛用于癌症治疗，因此在肿瘤治疗的各个阶段都发挥着重要作用。随着癌症治疗的不断进步，癌症治疗的总体疗效显著提高，患者的生存时间也大幅延长。近年来，一系列先进技术，包括纳米技术、基因编辑技术、实时无标记细胞分析（RTCA）技术和流式细胞术分析技术，已被开发并应用于中药治疗癌症的研究中，这些技术有效提高了中药的药用价值，加速了中药在癌症治疗方面的研究进展。因此，本文综述了这些先进技术在中药治疗癌症中的应用。我们希望这篇综述能为中药治疗癌症提供良好的指导。
