Muğla Sıtkı Koçman University Faculty of Medicine, Department of Ophthalmology, Muğla, Turkey.
Turk J Ophthalmol. 2022 Oct 28;52(5):318-323. doi: 10.4274/tjo.galenos.2021.22465.
To assess the central corneal thickness (CCT) with 5 different devices, evaluate the repeatability of the devices, and determine the possible relationship between thickness values and sex.
The study included 308 eyes of 154 patients (76 women, 78 men) between the ages of 18-30 who presented to the Ophthalmology Clinic of Muğla Sıtkı Koçman University Training and Research Hospital. Autorefractor (Topcon, Japan), ultrasound pachymetry (UP) (Ceniscan, USA), high-resolution Pentacam (Oculus, USA), anterior segment-optical coherence tomography (AS-OCT) (Optovue, USA), and Spectralis AS-OCT (Heidelberg, Germany) measurements were assessed.
The mean age of the study participants was 23.2±0.2 years and the mean CCT was 540±14.1 μm, with no statistically significant difference in CCT between sexes (p>0.05). Mean CCT values were 557.0±26.7 μm with the autorefractor, 543.6±32.9 μm with UP, 533.8±30.2 μm with the Oculus Pentacam, 519.8±30.1 μm with Optovue AS-OCT, and 547.5±31.6 μm with Heidelberg AS-OCT. Pairwise comparisons between devices showed that the Optovue AS-OCT gave significantly lower CCT measurements than the autorefractor and Heidelberg AS-OCT device (p=0.027 and p=0.033, respectively). The coefficient of repeatability for autorefractor, UP, high-resolution Pentacam, Optovue AS-OCT, and Heidelberg AS-OCT CCT measurements were 1.51%, 2.46%, 3.72%, 2.57%, and 3.34%, respectively.
Measurements made with five different devices showed that CCT was comparable and clinically usable. However, it was determined that the Optovue AS-OCT showed lower CCT values compare to other devices. When compared in terms of repeatability, it was found to be lower in the Pentacam than other devices.
使用 5 种不同的设备评估中央角膜厚度（CCT），评估设备的可重复性，并确定厚度值与性别之间的可能关系。
该研究纳入了年龄在 18-30 岁之间的 154 名患者（76 名女性，78 名男性）的 308 只眼，他们均就诊于穆拉省 Sıtkı Koçman 大学培训与研究医院的眼科诊所。自动屈光仪（日本 Topcon）、超声角膜测厚仪（美国 Ceniscan）、高分辨率 Pentacam（美国 Oculus）、眼前节光学相干断层扫描（美国 Optovue）和 Spectralis AS-OCT（德国 Heidelberg）进行了评估。
研究参与者的平均年龄为 23.2±0.2 岁，平均 CCT 为 540±14.1μm，性别间 CCT 无统计学差异（p＞0.05）。自动屈光仪的平均 CCT 值为 557.0±26.7μm，超声角膜测厚仪为 543.6±32.9μm，Oculus Pentacam 为 533.8±30.2μm，Optovue AS-OCT 为 519.8±30.1μm，Heidelberg AS-OCT 为 547.5±31.6μm。设备间的两两比较显示，Optovue AS-OCT 给出的 CCT 测量值明显低于自动屈光仪和 Heidelberg AS-OCT 设备（分别为 p=0.027 和 p=0.033）。自动屈光仪、超声角膜测厚仪、高分辨率 Pentacam、Optovue AS-OCT 和 Heidelberg AS-OCT 的 CCT 测量值的重复性系数分别为 1.51%、2.46%、3.72%、2.57%和 3.34%。
使用 5 种不同设备进行的测量表明，CCT 是可比且临床可用的。然而，Optovue AS-OCT 与其他设备相比，显示出较低的 CCT 值。在可重复性方面，Pentacam 比其他设备的重复性差。
