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基于石英晶体微天平的手性传感表面纳米结构设计

Design of surface nanostructures for chirality sensing based on quartz crystal microbalance.

作者信息

Ma Yinglin, Xiao Xiangyun, Ji Qingmin

机构信息

Herbert Gleiter Institute for Nanoscience, School of Materials Science and Engineering, Nanjing University of Science and Technology, 200 Xiaolingwei, Nanjing, 210094, China.

出版信息

Beilstein J Nanotechnol. 2022 Oct 27;13:1201-1219. doi: 10.3762/bjnano.13.100. eCollection 2022.

DOI:10.3762/bjnano.13.100
PMID:36348938
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9623132/
Abstract

Quartz crystal microbalance (QCM) has been widely used for various sensing applications, including chirality detection due to the high sensitivity to nanogram or picogram mass changes, fast response, real-time detection, easy operation, suitability in different media, and low experimental cost. The sensing performance of QCM is dependent on the surface design of the recognition layers. Various strategies have been employed for studying the relationship between the structural features and the specific detection of chiral isomers. This review provides an overview of the construction of chiral sensing layers by various nanostructures and materials in the QCM system, which include organic molecules, supermolecular assemblies, inorganic nanostructures, and metal surfaces. The sensing mechanisms based on these surface nanostructures and the related potentials for chiral detection by the QCM system are also summarized.

摘要

石英晶体微天平（QCM）已广泛应用于各种传感应用，包括手性检测，这是由于其对纳克或皮克质量变化具有高灵敏度、响应快、可实时检测、操作简便、适用于不同介质且实验成本低。QCM的传感性能取决于识别层的表面设计。人们采用了各种策略来研究结构特征与手性异构体特异性检测之间的关系。本文综述了在QCM系统中通过各种纳米结构和材料构建手性传感层的情况，这些材料包括有机分子、超分子组装体、无机纳米结构和金属表面。还总结了基于这些表面纳米结构的传感机制以及QCM系统在手性检测方面的相关潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/27e24ec49c7f/Beilstein_J_Nanotechnol-13-1201-g013.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/3856d0794d39/Beilstein_J_Nanotechnol-13-1201-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/dfac8ae28a94/Beilstein_J_Nanotechnol-13-1201-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/881c35343e74/Beilstein_J_Nanotechnol-13-1201-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/61d176805931/Beilstein_J_Nanotechnol-13-1201-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/3796387d8855/Beilstein_J_Nanotechnol-13-1201-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/15d753d98de3/Beilstein_J_Nanotechnol-13-1201-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/6f8ca36afb17/Beilstein_J_Nanotechnol-13-1201-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/172531a33f6c/Beilstein_J_Nanotechnol-13-1201-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/61a1174d5b98/Beilstein_J_Nanotechnol-13-1201-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/27e24ec49c7f/Beilstein_J_Nanotechnol-13-1201-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/86a653b60f6e/Beilstein_J_Nanotechnol-13-1201-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/91f678503a8a/Beilstein_J_Nanotechnol-13-1201-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/3856d0794d39/Beilstein_J_Nanotechnol-13-1201-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/dfac8ae28a94/Beilstein_J_Nanotechnol-13-1201-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/881c35343e74/Beilstein_J_Nanotechnol-13-1201-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/61d176805931/Beilstein_J_Nanotechnol-13-1201-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/3796387d8855/Beilstein_J_Nanotechnol-13-1201-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/15d753d98de3/Beilstein_J_Nanotechnol-13-1201-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/6f8ca36afb17/Beilstein_J_Nanotechnol-13-1201-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/172531a33f6c/Beilstein_J_Nanotechnol-13-1201-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/61a1174d5b98/Beilstein_J_Nanotechnol-13-1201-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cf7/9623132/27e24ec49c7f/Beilstein_J_Nanotechnol-13-1201-g013.jpg

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