Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Division of Immunology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Immunity. 2022 Nov 8;55(11):1978-1980. doi: 10.1016/j.immuni.2022.10.009.
RORγt regulatory T (Treg) cells are critical toward maintaining gut immune tolerance. In recent studies published in Nature, Kedmi et al., Lyu et al., and Akagbosu et al. describe MHCIIRORγt antigen-presenting cells that mediate RORγt Treg cell differentiation but propose disparate identities for these cells.
RORγt 调节性 T（Treg）细胞对于维持肠道免疫耐受至关重要。在最近发表在《自然》杂志上的 Kedmi 等人、Lyu 等人和 Akagbosu 等人的研究中，描述了 MHCIIRORγt 抗原呈递细胞介导 RORγt Treg 细胞分化，但对这些细胞提出了不同的身份。
