School of Petrochemical Engineering, Liaoning Petrochemical University, Fushun 113001, China.
Jiangsu Co-Innovation Center for Efficient Processing and Utilization of Forest Resources and Joint International Research Lab of Lignocellulosic Functional Materials, Nanjing Forestry University, Nanjing 210037, China.
Biosensors (Basel). 2022 Oct 28;12(11):937. doi: 10.3390/bios12110937.
In the real world, analytes usually exist in complex systems, and this makes direct detection by surface-enhanced Raman spectroscopy (SERS) difficult. Thin layer chromatography tandem with SERS (TLC-SERS) has many advantages in analysis such as separation effect, instant speed, simple process, and low cost. Therefore, the TLC-SERS has great potential for detecting analytes in mixtures without sample pretreatment. The review demonstrates TLC-SERS applications in diverse analytical relevant topics such as environmental pollutants, illegal additives, pesticide residues, toxic ingredients, biological molecules, and chemical substances. Important properties such as stationary phase, separation efficiency, and sensitivity are discussed. In addition, future perspectives for improving the efficiency of TLC-SERS in real sample detecting are outlined.
在现实世界中，分析物通常存在于复杂的体系中，这使得表面增强拉曼光谱（SERS）的直接检测变得困难。薄层色谱与 SERS 的串联（TLC-SERS）在分析方面具有许多优势，如分离效果、即时速度、简单的过程和低成本。因此，TLC-SERS 具有在无需样品预处理的情况下检测混合物中分析物的巨大潜力。本综述展示了 TLC-SERS 在各种分析相关主题中的应用，如环境污染物、非法添加剂、农药残留、有毒成分、生物分子和化学物质。讨论了重要的性质，如固定相、分离效率和灵敏度。此外，还概述了改善 TLC-SERS 在实际样品检测中效率的未来展望。
