Kwon Jun, Ko Hyoung Joon, Yang Myoung Hwan, Park Chul, Park Se Chang
Laboratory of Aquatic Biomedicine, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea.
Department of Veterinary Internal Medicine, Jeonbuk National University, Iksan 54596, Korea.
Vet Sci. 2022 Oct 27;9(11):592. doi: 10.3390/vetsci9110592.
Otitis externa, a common disease in dogs, has different etiologies. is a Gram-positive bacterium that frequently causes opportunistic ear infections. Here, we determined the distribution of in canine otitis externa via time-of-flight mass spectrometry and biochemical tests and evaluated their resistance patterns to 10 commonly used antibiotics. Among the 197 isolates, (48.7%; 96/197) was the most common, followed by (21.3%; 42/197), (11.7%; 23/197), (10.7%; 21/197), (3.6%; 7/197), (2.5%; 5/197), (1.0%; 2/197), and (0.5%; 1/197). All isolates were tested for antibiotic resistance using the Kirby-Bauer disc diffusion method. strains were highly resistant to erythromycin (45.8%) and rifampin (34.3%) but were generally susceptible to penicillin class antibiotics. In contrast, isolates were highly resistant to penicillin class antibiotics (ampicillin, 61.9%; penicillin, 71.4%). Most importantly, demonstrated high resistance to most of the antibiotics used in this study. Multidrug resistance was found in 28.4% of the isolates (56/197). This study shows prevalence and antibiotics resistance profiles of species in canine chronic otitis externa. The results can contribute to establish therapeutic strategies of infections and be used as a comparable index of antibiotic resistance of in the future.
外耳道炎是犬类常见疾病，病因各异。[细菌名称1]是一种革兰氏阳性菌，常引发机会性耳部感染。在此，我们通过飞行时间质谱法和生化试验确定了[细菌名称1]在犬外耳道炎中的分布情况，并评估了它们对10种常用抗生素的耐药模式。在197株分离菌株中，[细菌名称1]最为常见（48.7%；96/197），其次是[细菌名称2]（21.3%；42/197）、[细菌名称3]（11.7%；23/197）、[细菌名称4]（10.7%；21/197）、[细菌名称5]（3.6%；7/197）、[细菌名称6]（2.5%；5/197）、[细菌名称7]（1.0%；2/197）和[细菌名称8]（0.5%；1/197）。使用 Kirby - Bauer 纸片扩散法对所有分离菌株进行了抗生素耐药性检测。[细菌名称1]菌株对红霉素（45.8%）和利福平（34.3%）高度耐药，但对青霉素类抗生素普遍敏感。相比之下，[细菌名称2]分离株对青霉素类抗生素（氨苄西林，61.9%；青霉素，71.4%）高度耐药。最重要的是，[细菌名称3]对本研究中使用的大多数抗生素表现出高度耐药。在28.4%的分离株（56/197）中发现了多重耐药性。本研究显示了犬慢性外耳道炎中[细菌名称]物种的流行情况和抗生素耐药谱。这些结果有助于制定[细菌名称]感染的治疗策略，并在未来用作[细菌名称]抗生素耐药性的可比指标。
