Moon Bo-Youn, Ali Md Sekendar, Choi Ji-Hyun, Heo Ye-Eun, Lee Yeon-Hee, Kang Hee-Seung, Kim Tae-Sun, Yoon Soon-Seek, Moon Dong-Chan, Lim Suk-Kyung
Bacterial Disease Division, Animal and Plant Quarantine Agency, 177 Hyeksin 8-ro, Gimcheon-si 39660, Republic of Korea.
Public Health and Environment Institute of Gwangju, Gwangju 14502, Republic of Korea.
Microorganisms. 2023 Dec 15;11(12):2991. doi: 10.3390/microorganisms11122991.
spp. are typically found in the gastrointestinal tracts of humans and animals. However, they have the potential to produce opportunistic infections that can be transmitted to humans or other animals, along with acquired antibiotic resistance. In this study, we aimed to investigate the antimicrobial resistance profiles of and isolates obtained from companion animal dogs and cats in Korea during 2020-2022. The resistance rates in towards most of the tested antimicrobials were relatively higher than those in isolated from dogs and cats. We found relatively higher resistance rates to tetracycline (65.2% vs. 75.2%) and erythromycin (39.5% vs. 49.6%) in isolated from cats compared to those from dogs. However, in , the resistance rates towards tetracycline (35.6% vs. 31.5%) and erythromycin (40.3% vs. 35.2%) were comparatively higher for dog isolates than cats. No or very few and isolates were found to be resistant to daptomycin, florfenicol, tigecycline, and quinupristin/dalfopristin. Multidrug resistance (MDR) was higher in recovered from cats (44%) and dogs (33.9%) than in isolated from cats (24.1%) and dogs (20.5%). Moreover, MDR patterns in isolates from dogs (27.2%) and cats (35.2%) were shown to encompass five or more antimicrobials. However, isolates from dogs (at 13.4%) and cats (at 14.8%) were resistant to five or more antimicrobials. Taken together, the prevalence of antimicrobial-resistant enterococci in companion animals presents a potential public health concern.
某些菌种通常存在于人类和动物的胃肠道中。然而，它们有可能引发机会性感染，并可能与获得性抗生素耐药性一起传播给人类或其他动物。在本研究中，我们旨在调查2020年至2022年期间从韩国伴侣动物猫和狗身上分离得到的某些菌种和另一些菌种的抗菌药物耐药谱。某些菌种对大多数测试抗菌药物的耐药率相对高于从猫和狗身上分离出的另一些菌种。我们发现，与从狗身上分离出的某些菌种相比，从猫身上分离出的某些菌种对四环素（65.2%对75.2%）和红霉素（39.5%对49.6%）的耐药率相对较高。然而，在另一些菌种中，狗分离株对四环素（35.6%对31.5%）和红霉素（40.3%对35.2%）的耐药率相对高于猫分离株。未发现或极少发现某些菌种和另一些菌种的分离株对达托霉素、氟苯尼考、替加环素和奎奴普丁/达福普汀耐药。从猫（44%）和狗（33.9%）身上分离出的某些菌种的多重耐药性（MDR）高于从猫（24.1%）和狗（20.5%）身上分离出的另一些菌种。此外，从狗（27.2%）和猫（35.2%）身上分离出的某些菌种的MDR模式显示包含五种或更多抗菌药物。然而，从狗（13.4%）和猫（14.8%）身上分离出的另一些菌种对五种或更多抗菌药物耐药。综上所述，伴侣动物中耐抗菌药物肠球菌的流行存在潜在的公共卫生问题。
