Center for Human Sleep Science, Department of Psychology, University of California, Berkeley, CA, USA.
Department of Nutritional Sciences, King's College London, London, UK.
Nat Commun. 2022 Nov 19;13(1):7116. doi: 10.1038/s41467-022-34503-2.
How people wake up and regain alertness in the hours after sleep is related to how they are sleeping, eating, and exercising. Here, in a prospective longitudinal study of 833 twins and genetically unrelated adults, we demonstrate that how effectively an individual awakens in the hours following sleep is not associated with their genetics, but instead, four independent factors: sleep quantity/quality the night before, physical activity the day prior, a breakfast rich in carbohydrate, and a lower blood glucose response following breakfast. Furthermore, an individual's set-point of daily alertness is related to the quality of their sleep, their positive emotional state, and their age. Together, these findings reveal a set of non-genetic (i.e., not fixed) factors associated with daily alertness that are modifiable.
人们在睡眠后的数小时内如何醒来并恢复警觉状态与他们的睡眠、饮食和运动方式有关。在这里，通过对 833 对双胞胎和遗传上无关的成年人进行前瞻性纵向研究，我们证明了个体在睡眠后数小时内的觉醒效果与遗传无关，而是与四个独立因素相关：前一晚的睡眠数量/质量、前一天的身体活动、富含碳水化合物的早餐，以及早餐后较低的血糖反应。此外，个体的日常警觉设定点与其睡眠质量、积极的情绪状态和年龄有关。总的来说，这些发现揭示了一组与日常警觉相关的非遗传（即非固定）因素，这些因素是可以改变的。
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