伊朗南部沿海地区中老年人群的糖尿病前期、糖尿病及相关心血管代谢危险因素;班达雷-孔队列研究

Pre-diabetes, Diabetes Mellitus and Related Cardio-metabolic Risk Factors in the Southern Coastal Region of Iran Middle-aged and Elderly Population; Bandare-Kong Cohort Study.

作者信息

Ghaemmaghami Zahra, Eftekhar Ebrahim, Shahbazi Roghayeh, Nejatizadeh Azim, Shahmoradi Mehdi, Kheirandish Masoumeh

机构信息

Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.

Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

出版信息

Arch Iran Med. 2022 Jul 1;25(7):409-416. doi: 10.34172/aim.2022.68.

Abstract

BACKGROUND

To evaluate the prevalence of type 2 diabetes mellitus (T2DM), impaired fasting glucose (IFG), and its cardio-metabolic risk factors in the southern Iranian adult population.

METHODS

This is a population-based cross-sectional survey on 3944 middle-aged and elderly adults (35-70 years) from Bandare-Kong. The participants were recruited from 2016 to 2018 and the first phase data of the Bandare-Kong Cohort as a part of the PERSIAN Cohort were used for analysis.

RESULTS

Among the 3944 included adults, the age-adjusted prevalence of T2DM and IFG was 17.40% and 20.61%, respectively. Mean FPG was higher among those older than 55 years, females, rural residents, current cigarette smokers, hypertriglyceridemia, hypercholesterolemia, unemployed and low educational level in subjects with diabetes and pre-diabetes. T2DM and IFG were more prevalent in women and men, respectively. Also, those with higher waist circumference (WC), higher body mass index (BMI), lower educational levels, rural residents, former cigarette smokers, hypertension (HTN), hypercholesterolemia, hypertriglyceridemia and age older 45 years, had a higher T2DM and IFG prevalence. Multivariable regression analysis showed that older age, higher WC, HTN and hypertriglyceridemia and living in rural regions were statistically significant predictors of T2DM and pre-diabetes while BMI≥25 kg/m was the only significant risk factor for IFG.

CONCLUSION

The current study illustrated that T2DM and IFG have a high prevalence among the middle-aged and elderly adult Iranian population, particularly in rural dwellers. Hence, prevention strategies should be implemented to reduce diabetes and pre-diabetes, especially in rural areas.

摘要

背景

评估伊朗南部成年人群中2型糖尿病(T2DM)、空腹血糖受损(IFG)及其心血管代谢危险因素的患病率。

方法

这是一项基于人群的横断面调查,对象为来自Bandare-Kong的3944名中老年人(35 - 70岁)。参与者于2016年至2018年招募,Bandare-Kong队列的第一阶段数据作为波斯队列的一部分用于分析。

结果

在3944名纳入的成年人中,T2DM和IFG的年龄调整患病率分别为17.

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