Park Sunghae, Choi Gyu-Seong, Kim Jong Man, Lee Sanghoon, Joh Jae-Won, Rhu Jinsoo
Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Int J Bioprint. 2022 Aug 24;8(4):609. doi: 10.18063/ijb.v8i4.609. eCollection 2022.
The application of three-dimensional (3D) printing has been increasing and we invented cost-effective and time-saving 3D printed model of intra-abdominal cavity which was utilized in liver transplantation (LT) to prevent large-for-size syndrome. 3D printings were performed on potential adult recipients with small cavity and pediatric patients scheduled for transplantation during July 2020 - September 2021. Based on the computed tomography of the recipient, the inner surface of the abdominal cavity was outlined. The line was marked with a distance of 1 - 3 cm. Then, the outlined data were reconstructed as a 3D model and printed by a fused deposition modeling type 3D printer with a thickness of 2 mm. Pillars and footings for holding the lines were printed and assembled altogether. During deceased donor organ procurement, the size of the graft was compared to that of the printed model. For living donor LT, preoperatively planned liver graft was printed and was physically placed into the 3D printed abdominal cavity. All the 16 cases with 3D printed abdominal cavity showed appropriate fitting of the donor's liver graft to both the 3D printed model and actual recipient's abdominal cavity with no large-for-size syndrome after LT. Median time for manufacturing the model was 576 min (IQR 434 - 680) and estimated median cost for the filament was US$ 1.6 (IQR 1.2 - 1.7). The 3D printed abdominal cavity model can be manufactured in <10 h and was useful for preventing large-for-size syndrome in small-sized recipients.
三维(3D)打印的应用一直在增加,我们发明了一种经济高效且节省时间的腹腔3D打印模型,该模型用于肝移植(LT)以预防小肝综合征。在2020年7月至2021年9月期间,对潜在的小腹腔成年受者和计划进行移植的儿科患者进行了3D打印。根据受者的计算机断层扫描,勾勒出腹腔的内表面。以1 - 3厘米的间距标记线条。然后,将勾勒出的数据重建为3D模型,并由一台厚度为2毫米的熔融沉积成型型3D打印机进行打印。打印并组装用于固定线条的支柱和底座。在已故供体器官获取过程中,将移植物的大小与打印模型的大小进行比较。对于活体供体肝移植,术前规划的肝移植物被打印出来,并实际放入3D打印的腹腔中。所有16例使用3D打印腹腔的病例均显示供体肝移植物与3D打印模型以及实际受者腹腔均适配良好,肝移植后未出现小肝综合征。制造模型的中位时间为576分钟(四分位间距434 - 680),细丝的估计中位成本为1.6美元(四分位间距1.2 - 1.7)。3D打印的腹腔模型可以在不到10小时内制造出来,对于预防小体型受者的小肝综合征很有用。
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