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中性粒细胞/淋巴细胞比值联合红细胞分布宽度在评估脓毒症急诊患者预后中的价值

The Value of Neutrophil/Lymphocyte Ratio Combined with Red Blood Cell Distribution Width in Evaluating the Prognosis of Emergency Patients with Sepsis.

作者信息

Lin Maosheng, Zhang Louwei, Tang Xuhua, Tang Yejiang

机构信息

Department of Emergency Medicine, Zhuji Affiliated Hospital of Wenzhou Medical University, Zhuji, Zhejiang 311800, China.

出版信息

Emerg Med Int. 2022 Nov 10;2022:1673572. doi: 10.1155/2022/1673572. eCollection 2022.

DOI:10.1155/2022/1673572
PMID:36406930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9671714/
Abstract

Sepsis is a dysfunction of various organs caused by a dysfunctional host response induced by infection. In recent years, the mortality rate of sepsis patients, especially the mortality rate of septic shock patients still remains high. Due to the complexity and heterogeneity of sepsis, there is currently a lack of clinical biomarkers that can be widely used for the early assessment of sepsis. In order to find more concise and accurate biomarkers for timely and adequate intervention in sepsis, we explored the value of neutrophil/lymphocyte ratio (NLR) combined with red blood cell distribution width (RDW) in assessing the prognosis of emergency sepsis patients. The results showed that NLR and RDW were closely related to the prognosis of emergency sepsis patients. The combination of the two can evaluate the prognosis of patients with emergency sepsis, which deserves close attention from clinicians.

摘要

脓毒症是由感染引起的宿主反应失调导致的多器官功能障碍。近年来,脓毒症患者的死亡率,尤其是感染性休克患者的死亡率仍然居高不下。由于脓毒症的复杂性和异质性,目前缺乏可广泛用于脓毒症早期评估的临床生物标志物。为了寻找更简洁准确的生物标志物以便对脓毒症进行及时充分的干预,我们探讨了中性粒细胞/淋巴细胞比值(NLR)联合红细胞分布宽度(RDW)在评估急诊脓毒症患者预后中的价值。结果表明,NLR和RDW与急诊脓毒症患者的预后密切相关。两者联合可评估急诊脓毒症患者的预后,值得临床医生密切关注。

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Hospital-related costs of sepsis around the world: A systematic review exploring the economic burden of sepsis.全球脓毒症相关的医院费用:一项旨在探讨脓毒症经济负担的系统综述。
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Early Biomarker Signatures in Surgical Sepsis.手术相关性脓毒症的早期生物标志物特征。
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Immunomodulatory and Therapeutic Effects of Mesenchymal Stem Cells on Organ Dysfunction in Sepsis.间充质干细胞对脓毒症器官功能障碍的免疫调节及治疗作用
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