Department of Respiratory and Critical Care Medicine, Ningbo First Hospital, Ningbo, China.
Front Public Health. 2022 Nov 3;10:1038141. doi: 10.3389/fpubh.2022.1038141. eCollection 2022.
There is a strong correlation between dietary intake and allergic diseases. Ultra-processed foods (UPFs) are gradually becoming dominant worldwide and causing health problems for children and adults. We hope to determine whether links exist between UPFs and allergic symptoms.
We investigated data from 2,736 children (16-19 years) and 4,256 adults (≥20 years) from the National Health and Nutritional Examination Survey (NHANES) 2005-2006. The associations between the mean UPFs contribution to total energy intake and all allergic symptoms (IgE, current asthma, allergy, rash, sneeze, wheeze, eczema, and hay fever) were estimated by weighted multivariate logistic regression.
Logistic regression analysis showed UFPs were negatively associated with IgE levels in children. Those with higher quartiles had a reduced risk from 16% (OR, 0.84, 95%CI, 0.55 to 1.28) to 34% (OR, 0.66, 95%CI, 0.49 to 0.89), p for trend = 0.006. UPFs were also positively related to current asthma in children with an increased risk of 11% (OR, 1.11, 95%CI, 0.79 to 1.56) to 76% (OR, 1.76, 95%CI, 1.10 to 2.82), p for trend = 0.0393. UPFs were also associated with eczema in girls. But there was no association observed between UPFs and allergic symptoms in adults.
Our results suggested that UPFs assessed by the NOVA system were associated with IgE, current asthma in children, and eczema in girls. These results further support the need to test the association of modern dietary patterns with allergic symptoms.
饮食摄入与过敏疾病之间存在很强的相关性。超加工食品（UPFs）在全球范围内逐渐占据主导地位，给儿童和成人的健康带来问题。我们希望确定 UPFs 是否与过敏症状之间存在关联。
我们调查了来自 2005-2006 年全国健康和营养检查调查（NHANES）的 2736 名儿童（16-19 岁）和 4256 名成年人（≥20 岁）的数据。通过加权多变量逻辑回归估计 UPFs 对总能量摄入的平均贡献与所有过敏症状（IgE、当前哮喘、过敏、皮疹、打喷嚏、喘息、湿疹和花粉热）之间的关联。
逻辑回归分析表明 UPFs 与儿童 IgE 水平呈负相关。四分位组越高，风险从 16%（OR，0.84，95%CI，0.55 至 1.28）降低至 34%（OR，0.66，95%CI，0.49 至 0.89），趋势 P 值=0.006。UPFs 还与儿童当前哮喘呈正相关，风险增加 11%（OR，1.11，95%CI，0.79 至 1.56）至 76%（OR，1.76，95%CI，1.10 至 2.82），趋势 P 值=0.0393。UPFs 还与女孩的湿疹有关。但在成年人中，UPFs 与过敏症状之间没有关联。
我们的结果表明，通过 NOVA 系统评估的 UPFs 与 IgE、儿童当前哮喘和女孩湿疹有关。这些结果进一步支持需要测试现代饮食模式与过敏症状之间的关联。
