Glaucoma Fellow - JPM Rotary Eye Hospital, Bidanasi, Cuttack, India.
Managing Director - Kar Vision Eye Hospital, Bhubaneswar, India.
Indian J Ophthalmol. 2022 May;70(5):1594-1598. doi: 10.4103/ijo.IJO_2433_21.
To assess the comparability of ocular biometry measurements and refractive outcomes between ANTERION and IOL Master 700.
This comparative prospective study was conducted from December 2020 to February 2021. A total of 225 patients who had cataracts were enrolled for the study and different parameters such as anterior keratometry (Steep K, Flat K) with axis, Sim K, central corneal thickness (CCT), aqueous depth (AQD), lens thickness (LT), and axial length (AL), white-to-white (WTW) were evaluated in IOL master 700 first and then with ANTERION. Finally, 203 patients completed the 6-week follow-up and the postoperative refraction was done at the 6 week. To assess the agreement between the devices, intraclass coefficient (ICC) and Bland-Altman analysis with 95% limits of agreement (LoA) were used. To analyze the agreement for postoperative residual refractive error between the two devices, Kappa statistics were used.
The mean difference for steep K, flat K, and Sim K between ANTERION and IOL Master 700 were - 0.18 +/-0.26 D, -0.13+/- 0.28D, -0.15 +/-0.23, respectively. The CCT, ACD, and LT also showed excellent agreement (ICC > 0.9) but the similarity for the keratometry axis was not up to the mark (ICC = 0.794). For postoperative refractive outcomes, the Kappa value was 0.437, indicating moderate agreement.
: ANTERION showed a good agreement for the majority of parameters with IOLMaster 700 in measuring ocular biometry, except for the keratometry. The accuracy of the intraocular lens power calculations was clinically acceptable with both biometers though the IOL power given by ANTERION remained slightly on the hypermetropic side.
评估 ANTERION 与 IOL Master 700 之间的眼生物测量和屈光结果的可比性。
本研究为前瞻性比较研究，于 2020 年 12 月至 2021 年 2 月进行。共纳入 225 例白内障患者，分别使用 IOL Master 700 测量前角膜曲率（陡 K、平 K 和轴）、Sim K、中央角膜厚度（CCT）、房水深度（AQD）、晶状体厚度（LT）和眼轴（AL）等参数，然后使用 ANTERION 重复测量。最后，203 例患者完成 6 周随访，术后 6 周行屈光检查。采用组内相关系数（ICC）和 Bland-Altman 分析（95%一致性界限）评估设备间的一致性，采用 Kappa 统计分析评估两种设备间术后残余屈光误差的一致性。
ANTERION 与 IOL Master 700 之间的陡 K、平 K 和 Sim K 的平均差异分别为-0.18+/-0.26 D、-0.13+/-0.28 D 和-0.15+/-0.23 D。CCT、ACD 和 LT 也具有很好的一致性（ICC＞0.9），但角膜曲率轴的相似性不理想（ICC=0.794）。术后屈光结果的 Kappa 值为 0.437，表明具有中度一致性。
ANTERION 在测量眼生物参数方面与 IOLMaster 700 大多数参数具有良好的一致性，除了角膜曲率。两种生物测量仪的人工晶状体屈光度计算的准确性均为临床可接受，但 ANTERION 给出的人工晶状体屈光度稍偏远视。
