Harugop Anil S, Walia Akriti, Havaldar Rajesh Radhakrishna, Mudhol R S
Department of ENT and Head and Neck Surgery, J. N. Medical College, KLE Academy Of Higher Education and Research, Belagavi, Karnataka India.
Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):1033-1036. doi: 10.1007/s12070-020-02095-2. Epub 2020 Sep 1.
Allergic rhinitis is one of the most rampant diseases in the world and many studies have been conducted to find its risk factors. Various studies have shown that there is a correlation between allergic rhinitis and increased Body Mass Index (BMI). Obesity has several effects on the immune system that could play a major role in increasing allergic disease. Allergic rhinitis is known to produce mild eosinophilia. The purpose of this study is to assess the correlation between BMI and allergic rhinitis using the Absolute Eosinophil Count (AEC). Over a period of 6 months, 55 cases of allergic rhinitis were selected. The patients were investigated by Absolute Eosinophil Count and their Body Mass Index values were calculated based on weight and height measurement. There was a positive correlation between Absolute Eosinophil Count and BMI with a value of < 0.0001 which in turn revealed a positive correlation between BMI and allergy. We conclude that patients with high BMI are more prone to allergic rhinitis and have higher Absolute Eosinophil Counts probably due to the immunological effects of adipose tissue on the progress of the allergic disease.
变应性鼻炎是世界上最常见的疾病之一，人们已经进行了许多研究来寻找其危险因素。各种研究表明，变应性鼻炎与体重指数（BMI）升高之间存在关联。肥胖对免疫系统有多种影响，这可能在变应性疾病的增加中起主要作用。已知变应性鼻炎会导致轻度嗜酸性粒细胞增多。本研究的目的是使用绝对嗜酸性粒细胞计数（AEC）评估BMI与变应性鼻炎之间的相关性。在6个月的时间里，选取了55例变应性鼻炎患者。通过绝对嗜酸性粒细胞计数对患者进行调查，并根据体重和身高测量计算其BMI值。绝对嗜酸性粒细胞计数与BMI之间存在正相关，值<0.0001，这反过来又揭示了BMI与过敏之间的正相关。我们得出结论，BMI高的患者更容易患变应性鼻炎，并且绝对嗜酸性粒细胞计数更高，这可能是由于脂肪组织对变应性疾病进展的免疫影响。
