University of Illinois College of Veterinary Medicine, Urbana, Illinois, USA.
Can Vet J. 2022 Dec;63(12):1221-1225.
Urothelial carcinoma (UC), or transitional cell carcinoma, is the most common canine urothelial malignancy in dogs. Females are predisposed and provide a challenge for diagnostic tumor sampling. The objectives of this study were to investigate the use and tolerability of vaginal swab cytology for UC diagnosis. Five dogs were identified with non-diagnostic urine sediment cytology and UC diagnosed on vaginal cytology with confirmation by another means. All patients tolerated the vaginal swab with minimal restraint. This study confirms the potential of vaginal swab cytology as a simple, inexpensive, and well-tolerated means for lower urinary tract UC diagnosis in female dogs. Key clinical message: Vaginal swab cytology is a non-invasive, low-cost method of obtaining a sample for cytological assessment for UC.
尿路上皮癌（UC），又称移行细胞癌，是犬最常见的尿路上皮恶性肿瘤。雌性犬易患此病，且这给诊断性肿瘤取样带来了挑战。本研究旨在探讨阴道拭子细胞学检查在 UC 诊断中的应用和耐受性。本研究共纳入 5 例尿液沉渣细胞学检查结果不明确但被诊断为 UC 的犬，这些犬的阴道细胞学检查结果均得到了进一步的确认。所有患者均能耐受阴道拭子检查，仅需轻微的约束。本研究证实了阴道拭子细胞学检查作为一种简单、经济且耐受性良好的方法，可用于诊断雌性犬下尿路 UC。关键临床信息：阴道拭子细胞学检查是一种非侵入性、低成本的方法，可用于获取细胞学评估 UC 的样本。
