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夜班工作对心血管危险因素的影响我们了解多少?伞式综述。

What do we know about the effect of night-shift work on cardiovascular risk factors? An umbrella review.

机构信息

Department of Occupational Epidemiology, French Research and Safety Institute for the Prevention of Occupational Accidents and Diseases (INRS), Vandœuvre-les-Nancy, France.

UMR1295, Paul Sabatier III University - INSERM CERPOP: Centre for Epidemiology and Research in POPulation Health, Toulouse, France.

出版信息

Front Public Health. 2022 Nov 23;10:1034195. doi: 10.3389/fpubh.2022.1034195. eCollection 2022.

Abstract

OBJECTIVE

To evaluate the existing evidence on the effect of night-shift work and its subtypes (permanent and rotating) on cardiovascular risk factors: diabetes, lipid disorders, being overweight, hypertension, smoking habits, sedentariness, and occupational psychosocial stressors.

METHOD

A Web of Sciences and Cochrane review library search was conducted to identify systematic reviews with or without meta-analysis dealing with the quantification of the link between night-shift work and the studied cardiovascular risk factors in working populations. We used the AMSTAR 2 to evaluate the quality of each review. The main results of the included systematic reviews were compiled in a summary structured around the different cardiovascular risk factors.

RESULTS

After selection, 33 systematic reviews were included: nine for diabetes, four for lipid disorders, nine for being overweight, four for hypertension, two for smoking habits, three for occupational psychosocial stressors and two for sedentariness. The results confirmed an excess risk of diabetes of about 10% regardless of the type of night work. A stated excess risk of being overweight at around 25% was also highlighted for shift workers overall, which could reach 38% among night-shift workers. An increased risk of obesity, estimated at 5% for night-shift workers and at 18% for rotating shift workers, was observed. An excess risk of hypertension was estimated at around 30% when considering the broad definition of shift work and when night periods were included in rotating shifts. The literature provided inconsistent results for the link between lipid disorders and night-shift work. Shift workers appeared to be more likely to smoke. The link between shift work and occupational psychosocial stressors was scarcely explored in the available studies. Sedentariness was scarcely considered in systematic reviews, which prevents any firm conclusions.

CONCLUSION

The consequences of night work in terms of diabetes, being overweight/obesity and hypertension are established. Monitoring of these cardiovascular risk factors for these night-shift workers could be implemented by practitioners. In contrast, the links with lipid disorders, sedentariness, smoking habits, and occupational psychosocial stressors warrant further investigation.

SYSTEMATIC REVIEW REGISTRATION

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021275212, PROSPERO (ID CRD42021275212).

摘要

目的

评估夜班工作及其亚型(永久性和轮班性)对心血管危险因素的影响的现有证据:糖尿病、血脂紊乱、超重、高血压、吸烟习惯、久坐不动和职业心理社会压力源。

方法

通过 Web of Sciences 和 Cochrane 评论库检索,以确定涉及夜班工作与工作人群中所研究心血管危险因素之间联系的定量分析的系统评价,无论是否进行荟萃分析。我们使用 AMSTAR 2 来评估每个评价的质量。将纳入的系统评价的主要结果编译为一个摘要,围绕不同的心血管危险因素进行组织。

结果

经过筛选,共纳入 33 项系统评价:9 项用于糖尿病,4 项用于血脂紊乱,9 项用于超重,4 项用于高血压,2 项用于吸烟习惯,3 项用于职业心理社会压力源,2 项用于久坐不动。结果证实,无论夜班类型如何,夜班工作者患糖尿病的风险增加约 10%。总体而言,轮班工作者超重的风险也被认为是 25%左右,而夜班工作者的风险可能高达 38%。观察到肥胖的风险增加,夜班工作者估计为 5%,轮班工作者估计为 18%。当考虑广泛的轮班工作定义并将夜间时段包括在轮班工作中时,高血压的风险估计约为 30%。文献中夜班工作与血脂紊乱之间的联系结果不一致。轮班工作者似乎更有可能吸烟。在现有研究中,夜班工作与职业心理社会压力源之间的联系几乎没有被探讨。系统评价很少考虑久坐不动的问题,这使得无法得出任何确定的结论。

结论

夜班工作在糖尿病、超重/肥胖和高血压方面的后果已得到确立。从业者可以为这些夜班工作者监测这些心血管危险因素。相比之下,夜班工作与血脂紊乱、久坐不动、吸烟习惯和职业心理社会压力源之间的联系需要进一步研究。

系统评价注册

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021275212,PROSPERO(ID CRD42021275212)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2109/9727235/47e884639195/fpubh-10-1034195-g0001.jpg

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