Geraili Ali, Badirzadeh Alireza, Sadeghi Maryam, Mousavi Seyed Mahmoud, Mousavi Parisa, Shahmoradi Zabihollah, Hosseini Sayed-Mohsen, Hejazi Seyed Hossein, Rafiei-Sefiddashti Raheleh
Tehran, Iran Department of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences.
Isfahan, Iran Department of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences.
J Parasit Dis. 2023 Mar;47(1):185-191. doi: 10.1007/s12639-022-01556-5. Epub 2022 Dec 11.
Toxoplasmosis has been categorized as one of the long-lasting protozoan parasitic infections. It affects almost one-third of the world's population. In recent years, several documented studies have elucidated that infected individuals have a remarkably higher incidence of distinct health problems and show various adverse effects. In the PCR-positive COVID-19 patients in Gonbad-e-Kavus, Kalaleh, and Minoodasht counties in the northern part of Iran from June 2021 to December 2021, we sought to investigate any potential relationships between the severity of COVID-19 symptoms and acute and latent toxoplasmosis caused by (). Whole blood samples of 161 COVID-19 patients with positive PCR. The samples were centrifuged to separate serum and screened for two important antibodies against (IgM and IgG) by using ELISA kits for human anti- IgM and IgG. Anti- IgM and IgG antibodies were detected in 8/161 (5.0%) and 42/161 (26.1%) COVID-19 patients, respectively. No significant relationships were found between IgM and IgG results with clinical signs, age, sex, contact with animals, comorbidities, and also the mortality rate of people with COVID-19. These findings showed that acute and latent toxoplasmosis infections are common among patients with COVID-19; however, no significant associations were found between toxoplasma infections and the symptoms of COVID-19. Therefore, toxoplasmosis is not considered a risk factor for COVID-19.
弓形虫病已被归类为长期存在的原生动物寄生虫感染之一。它影响着世界近三分之一的人口。近年来，多项有记录的研究表明，受感染个体出现明显健康问题的发生率显著更高，并表现出各种不良影响。在2021年6月至2021年12月期间伊朗北部贡巴德 - 卡武斯、卡拉莱和米努达斯ht县的PCR阳性COVID - 19患者中，我们试图调查COVID - 19症状的严重程度与由（）引起的急性和潜伏性弓形虫病之间的任何潜在关系。对161名PCR阳性的COVID - 19患者的全血样本进行检测。将样本离心以分离血清，并使用人抗 - IgM和IgG的ELISA试剂盒筛查针对（）的两种重要抗体（IgM和IgG）。在161名COVID - 19患者中，分别有8/161（5.0%）和42/161（26.1%）检测到抗 - IgM和抗 - IgG抗体。未发现抗 - IgM和IgG结果与临床体征、年龄、性别、与动物接触、合并症以及COVID - 19患者的死亡率之间存在显著关系。这些发现表明，急性和潜伏性弓形虫病感染在COVID - 19患者中很常见；然而，未发现弓形虫感染与COVID - 19症状之间存在显著关联。因此，弓形虫病不被认为是COVID - 19的危险因素。
