Department of Epidemiology University of North Carolina at Chapel Hill Chapel Hill NC.
Department of Epidemiology Rollins School of Public Health Atlanta GA.
J Am Heart Assoc. 2022 Dec 20;11(24):e027610. doi: 10.1161/JAHA.122.027610. Epub 2022 Dec 19.
Background Cardiovascular health (CVH) declines in young adulthood, and mood disorders commonly emerge during this life stage. This study examined the association between depression, anxiety, and CVH metrics among young adults. Methods and Results We conducted a cross-sectional analysis of participants aged 18 to 34 years who completed the Emory Healthy Aging Study Health History Questionnaire (n=875). We classified participants as having poor, intermediate, or ideal levels of the 8 CVH metrics using definitions set forth by the American Heart Association with adaptions when necessary. We defined depression and anxiety as absent, mild, or moderate to severe using standard cutoffs for Patient Health Questionnaire and General Anxiety Disorder scales. We used multivariable regression to examine the association between depression and anxiety and CVH, adjusting for age, sex, race and ethnicity, income, and education. The mean participant age was 28.3 years, and the majority identified as women (724; 82.7%); 129 (14.7%) participants had moderate to severe anxiety, and 128 (14.6%) participants had moderate to severe depression. Compared with those without anxiety, participants with moderate to severe anxiety were less likely to meet ideal levels of physical activity (adjusted prevalence ratio [aPR], 0.60 [95% CI, 0.44-0.82]), smoking (aPR, 0.90 [95% CI, 0.82-0.99]), and body mass index (aPR, 0.79 [95% CI, 0.66-0.95]). Participants with moderate to severe depression were less likely than those without depression to meet ideal levels of physical activity (aPR, 0.48 [95% CI, 0.34-0.69]), body mass index (aPR, 0.75 [95% CI, 0.61-0.91]), sleep (aPR, 0.79 [95% CI, 0.66-0.94]), and blood pressure (aPR, 0.92 [95% CI, 0.86-0.99]). Conclusions Anxiety and depression are associated with less ideal CVH in young adults. Interventions targeting CVH behaviors such as physical activity, diet, and sleep may improve both mood and CVH.
心血管健康（CVH）在年轻成年人中下降，而情绪障碍通常在此生命阶段出现。本研究探讨了年轻成年人中抑郁、焦虑与 CVH 指标之间的关系。
我们对完成埃默里健康老龄化研究健康史问卷的 18 至 34 岁参与者（n=875）进行了横断面分析。我们使用美国心脏协会的定义，必要时进行调整，将参与者的 8 项 CVH 指标分为较差、中等和理想水平。我们使用患者健康问卷和一般焦虑症量表的标准截断值将抑郁和焦虑定义为无、轻度或中重度。我们使用多变量回归来检查抑郁和焦虑与 CVH 的关系，调整年龄、性别、种族和民族、收入和教育。参与者的平均年龄为 28.3 岁，大多数为女性（724；82.7%）；129（14.7%）名参与者有中重度焦虑，128（14.6%）名参与者有中重度抑郁。与无焦虑者相比，中重度焦虑者更不可能达到理想的体力活动水平（调整后的患病率比 [aPR]，0.60 [95%CI，0.44-0.82]）、吸烟（aPR，0.90 [95%CI，0.82-0.99]）和体重指数（aPR，0.79 [95%CI，0.66-0.95]）。与无抑郁者相比，中重度抑郁者更不可能达到理想的体力活动水平（aPR，0.48 [95%CI，0.34-0.69]）、体重指数（aPR，0.75 [95%CI，0.61-0.91]）、睡眠（aPR，0.79 [95%CI，0.66-0.94]）和血压（aPR，0.92 [95%CI，0.86-0.99]）。
焦虑和抑郁与年轻成年人较差的 CVH 相关。针对体力活动、饮食和睡眠等 CVH 行为的干预措施可能会改善情绪和 CVH。
