Alenezi Shuliweeh, Alkhiri Aqeel, Hassanin Weaam, AlHarbi Amani, Al Assaf Munirah, Alzunaydi Norah, Alsharif Salma, Alhaidar Mohammad, Alnujide Abdulaziz, Alkathiri Fatimah, Alyousef Abdulaziz, Albassam Razan, Alkhamees Hadeel, Alyahya Ahmed S
Department of Psychiatry, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia.
Department of Psychiatry, King Saud University Medical City, King Saud University, Riyadh 12372, Saudi Arabia.
Behav Sci (Basel). 2022 Dec 14;12(12):509. doi: 10.3390/bs12120509.
Children with ASD have a wide spectrum of functional deficits in multiple neurodevelopmental domains. A multidisciplinary team assessment (MDT) is required to assess those deficits to help construct a multimodal intervention plan. This is a retrospective chart review of the assessment for children who were referred for an assessment of potential neurodevelopmental disorders. We reviewed 221 participants' charts from January 2019 to January 2020. The mean age of the children was 7.95 ± 3.69, while the mean age of the fathers and mothers was 37.31 ± 8.57 and 31.95 ± 6.93, respectively. Consanguinity was as high as 37.9% for the referred children with developmental delay who were first-degree related, and 13.2% of the parents were second-degree relatives. Approximately 26.6% of children had a family history of mental illness in first-degree relatives. ASD was the most commonly reported diagnosis post-assessment, and ADHD was the most common reported comorbidity at 64.3% and 88.5%, respectively. The MDT findings showed that 58% of children required moderate or higher assistance with toileting, 79.2% were unable to answer yes/no questions, and 86.8% were unable to understand "wh" questions. Only 26% of the nonverbal children had average IQ testing results, and 31% of verbal children did. In conclusion, the mean age of the children when assessed was above that recommended for early screening and intervention. An increased paternal and maternal age was noticeable. Consanguinity and a family history of mental disorders in first-degree relatives were high, attesting to a possible genetic risk.
患有自闭症谱系障碍(ASD)的儿童在多个神经发育领域存在广泛的功能缺陷。需要多学科团队评估(MDT)来评估这些缺陷,以帮助制定多模式干预计划。这是一项对被转介进行潜在神经发育障碍评估的儿童的评估进行的回顾性病历审查。我们回顾了2019年1月至2020年1月期间221名参与者的病历。儿童的平均年龄为7.95±3.69岁,而父亲和母亲的平均年龄分别为37.31±8.57岁和31.95±6.93岁。被转介的发育迟缓儿童中,一级亲属的近亲结婚率高达37.9%,13.2%的父母是二级亲属。约26.6%的儿童一级亲属有精神疾病家族史。评估后最常报告的诊断是ASD,最常见的共病是注意力缺陷多动障碍(ADHD),分别为64.3%和88.5%。多学科团队的评估结果显示,58%的儿童在如厕方面需要中度或更高程度的帮助,79.2%的儿童无法回答是/否问题,86.8%的儿童无法理解“wh”问题。只有26%的非语言儿童智商测试结果为平均水平,语言儿童的这一比例为31%。总之,接受评估时儿童的平均年龄高于早期筛查和干预建议的年龄。父母年龄增加明显。一级亲属中的近亲结婚率和精神障碍家族史较高,证明可能存在遗传风险。