Porfirio Maria Cristina, Campanile Roberta, Masi Gabriele, Purper-Ouakil Diane, Giovinazzo Silvia, Ascenzi Alessandra, Troisi Alfonso, Mazzone Luigi
Child Neurology and Psychiatry Unit, Tor Vergata Hospital, Fondazione PTV, Oxford Street 81, 00133 Rome, Italy.
Systems Medicine Department, University of Rome Tor Vergata, Montpellier Street 1, 00133 Rome, Italy.
Brain Sci. 2022 Nov 29;12(12):1631. doi: 10.3390/brainsci12121631.
Multiple studies support the relationship between ADHD and overweight/obesity in youth. Different mechanisms may be involved, such as temperamental and psychopathological factors. The aim of this study was to test the hypothesis that specific temperamental and psychopathological dimensions could mediate the relationship between ADHD and obesity. The sample included 100 children and adolescents (78 males and 22 females; age range 6 to 18 years; mean age 9.90 ± 2.5 years). The assessment procedure included Conners' Parent Rating Scale-Long (CPRS-R:L) as the inclusion criterion for ADHD diagnosis, the Child Behavior Checklist (CBCL), a dimensional measure for psychopathology, and the Junior Temperament and Character Inventory, which describes four temperamental dimensions: novelty seeking (NS), harm avoidance (HA), reward dependence (RD), and persistence (P). While in the whole ADHD sample, the highest scores were found in NS and the lowest in P, ADHD with overweight/obesity, compared to ADHD with normal weight, showed higher HA and RD, lower NS, and higher CBCL Internalizing scores. These findings suggest that ADHD youth with overweight/obesity present specific temperamental and psychopathological features compared to those without overweight/obesity. If confirmed in larger samples, using a control group without ADHD, these temperamental and psychological features may be helpful for an earlier recognition of ADHD patients at higher risk for obesity, and may represent possible targets for temperament-based preventive interventions and tailored treatment programs. These features should be included in the routine assessment of children and adolescents with ADHD and/or are overweight/obese.
多项研究证实了青少年注意力缺陷多动障碍(ADHD)与超重/肥胖之间的关联。可能涉及不同的机制,如气质和精神病理学因素。本研究的目的是检验特定的气质和精神病理学维度可能介导ADHD与肥胖之间关系的假设。样本包括100名儿童和青少年(78名男性和22名女性;年龄范围6至18岁;平均年龄9.90±2.5岁)。评估程序包括使用康纳斯父母评定量表-长式(CPRS-R:L)作为ADHD诊断的纳入标准、儿童行为检查表(CBCL)(一种精神病理学的维度测量方法)以及青少年气质与性格问卷,该问卷描述了四个气质维度:寻求新奇(NS)、避免伤害(HA)、奖赏依赖(RD)和坚持性(P)。在整个ADHD样本中,NS得分最高,P得分最低,与体重正常的ADHD患者相比,超重/肥胖的ADHD患者表现出更高的HA和RD、更低的NS以及更高的CBCL内化得分。这些发现表明,与没有超重/肥胖的ADHD青少年相比,超重/肥胖的ADHD青少年具有特定的气质和精神病理学特征。如果在更大样本中得到证实,使用无ADHD的对照组,这些气质和心理特征可能有助于早期识别肥胖风险较高的ADHD患者,并且可能代表基于气质的预防干预和量身定制治疗方案的可能目标。这些特征应纳入对患有ADHD和/或超重/肥胖的儿童和青少年的常规评估中。