金纳米颗粒在医用植入物改性中的抗菌性能：一项系统综述

Antibacterial Properties of Gold Nanoparticles in the Modification of Medical Implants: A Systematic Review.

作者信息

Zhan Xinxin, Yan Jianglong, Tang Hao, Xia Dandan, Lin Hong

机构信息

Department of Dental Materials, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing 100081, China.

Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA.

出版信息

Pharmaceutics. 2022 Nov 30;14(12):2654. doi: 10.3390/pharmaceutics14122654.

The widespread occurrence of bacterial infections and their increased resistance to antibiotics has led to the development of antimicrobial coatings for multiple medical implants. Owing to their desirable properties, gold nanoparticles (AuNPs) have been developed as antibacterial agents. This systematic investigation sought to analyze the antibacterial effects of implant material surfaces modified with AuNPs. The data from 27 relevant studies were summed up. The included articles were collected from September 2011 to September 2021. According to the retrieved literature, we found that medical implants modified by AuNPs have good antibacterial effects against gram-positive and gram-negative bacteria, and the antibacterial effects would be improved by near-infrared (NIR) radiation.