Sarantaki Antigoni, Kalogeropoulou Vasiliki Evangelia, Taskou Chrysoula, Nanou Christina, Lykeridou Aikaterini
Midwifery Department, University of West Attica, 12243 Athens, Greece.
Free-Lancer Midwife, 15123 Athens, Greece.
Vaccines (Basel). 2022 Nov 30;10(12):2055. doi: 10.3390/vaccines10122055.
Mass vaccination against COVID-19 is necessary to control the pandemic. COVID-19 vaccines are now recommended during pregnancy to prevent the disease. A systematic review of the literature in the electronic databases PubMed and EMBASE was performed and we aimed to investigate the attitude of documents towards COVID-19 vaccination and the prognostic factors of vaccination hesitation. A meta-analysis was also conducted to estimate the overall percentage of pregnant women who were willing to be vaccinated or had been vaccinated against COVID-19. A total of 18 studies were included in the review and meta-analysis. The acceptance rate of vaccination against COVID-19 among pregnant women ranged from 17.6% to 84.5%. The pooled proportion of acceptance of vaccination against COVID-19 in pregnant women was 0.53 (95% CI: 0.44-0.61). Predictors of acceptance of COVID-19 vaccination were older age, White race, occupational status, higher level of education, comorbidities, third trimester of pregnancy, influenza vaccination, knowledge about COVID-19, and confidence that vaccines for COVID-19 are safe and effective. The prevalence of COVID-19 vaccination in pregnant women is low. Targeted information campaigns are needed to increase vaccine education in this population.
大规模接种新冠疫苗对于控制疫情至关重要。目前建议在孕期接种新冠疫苗以预防该疾病。我们对电子数据库PubMed和EMBASE中的文献进行了系统综述，旨在调查文献对新冠疫苗接种的态度以及接种犹豫的预后因素。还进行了一项荟萃分析，以估计愿意接种或已接种新冠疫苗的孕妇的总体百分比。该综述和荟萃分析共纳入了18项研究。孕妇中新冠疫苗接种的接受率在17.6%至84.5%之间。孕妇接种新冠疫苗的合并接受比例为0.53（95%置信区间：0.44 - 0.61）。新冠疫苗接种接受度的预测因素包括年龄较大、白人种族、职业状况、教育程度较高、合并症、妊娠晚期、流感疫苗接种、对新冠的了解以及对新冠疫苗安全性和有效性的信心。孕妇中新冠疫苗接种的普及率较低。需要开展有针对性的宣传活动，以加强该人群的疫苗教育。
