Department of Public Health, University of Liège, Belgium.
Department of Pneumology, GIGAI3, University of Liège, Belgium.
Respir Med. 2023 Feb;207:107098. doi: 10.1016/j.rmed.2022.107098. Epub 2022 Dec 28.
Many studies exploring the factors associated with asthma-specific quality of life (QOL) have shown that asthma control is the main predictor of asthma-related QOL. However, to the best of our knowledge, no study has ever explored the individual impact of the five main symptoms of asthma (wheezing, dyspnea, chest tightness, cough and airway secretion) reported directly by the patient on asthma-related QOL. A cross-sectional study was conducted on untreated adult (≥18 years) asthmatics recruited from the Liege University Hospital Asthma Clinic (Belgium) for asthma diagnosis confirmation between 2018 and 2021 (n = 171). Multiple linear regression analysis demonstrated that dyspnea and chest tightness were the two leading factors associated with asthma-related QOL in a population of mild asthma.
许多研究探讨了与哮喘特异性生活质量（QOL）相关的因素，结果表明哮喘控制是哮喘相关 QOL 的主要预测因素。然而，据我们所知，尚无研究探讨过直接由患者报告的哮喘的五个主要症状（喘息、呼吸困难、胸闷、咳嗽和气道分泌物）对哮喘相关 QOL 的个体影响。本研究为横断面研究，于 2018 年至 2021 年期间在比利时列日大学医院哮喘诊所招募未接受治疗的成年（≥18 岁）哮喘患者（n=171）进行哮喘诊断确认。多线性回归分析表明，呼吸困难和胸闷是轻度哮喘人群中与哮喘相关 QOL 相关的两个主要因素。
