Xu Kezhu, Fang Qunling, Wang Jing, Hui Ailing, Xuan Shouhu
School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Modern Mechanics, University of Science and Technology of China, Hefei 230027, China.
Materials (Basel). 2022 Dec 31;16(1):387. doi: 10.3390/ma16010387.
Due to the abuse of antibiotics, the sensitivity of patients to antibiotics is gradually reduced. This work develops a FeO@SiO@Au/PDA nanochain which shows an interesting magnetic-field-induced improvement of its photothermal antibacterial property. First, SiO was wrapped on FeO nanospheres assembled in a chain to form a FeO@SiO nanocomposite with a chain-like nanostructure. Then, the magnetic FeO@SiO@Au/PDA nanochains were prepared using in situ redox-oxidization polymerization. Under the irradiation of an 808 nm NIR laser, the temperature rise of the FeO@SiO@Au/PDA nanochain dispersion was obvious, indicating that they possessed a good photothermal effect. Originating from the FeO, the FeO@SiO@Au/PDA nanochain showed a typical soft magnetic behavior. Both the NIR and magnetic field affected the antimicrobial performance of the FeO@SiO@Au/PDA nanochains. and were used as models to verify the antibacterial properties. The experimental results showed that the FeO@SiO@Au/PDA nanochains exhibited good antibacterial properties under photothermal conditions. After applying a magnetic field, the bactericidal effect was further significantly enhanced. The above results show that the material has a broad application prospect in inhibiting the growth of bacteria.
由于抗生素的滥用，患者对抗生素的敏感性逐渐降低。这项工作制备了一种FeO@SiO@Au/PDA纳米链，其展现出有趣的磁场诱导光热抗菌性能改善。首先，SiO包裹在组装成链状的FeO纳米球上，形成具有链状纳米结构的FeO@SiO纳米复合材料。然后，通过原位氧化还原聚合反应制备了磁性FeO@SiO@Au/PDA纳米链。在808 nm近红外激光照射下，FeO@SiO@Au/PDA纳米链分散液的温度明显升高，表明它们具有良好的光热效应。源于FeO，FeO@SiO@Au/PDA纳米链表现出典型的软磁行为。近红外光和磁场都影响FeO@SiO@Au/PDA纳米链的抗菌性能。以 和 作为模型来验证抗菌性能。实验结果表明，FeO@SiO@Au/PDA纳米链在光热条件下表现出良好的抗菌性能。施加磁场后，杀菌效果进一步显著增强。上述结果表明该材料在抑制细菌生长方面具有广阔的应用前景。
