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雅典成年人随机样本中的冠心病风险因素。雅典研究。

Coronary heart disease risk factors in a random sample of Athenian adults. The Athens Study.

作者信息

Moulopoulos S D, Adamopoulos P N, Diamantopoulos E I, Nanas S N, Anthopoulos L N, Iliadi-Alexandrou M

机构信息

Dept. of Clinical Therapeutics, U. of Athens, Greece.

出版信息

Am J Epidemiol. 1987 Nov;126(5):882-92. doi: 10.1093/oxfordjournals.aje.a114725.

Abstract

Risk factors for cardiovascular diseases not previously investigated in Greece were studied in a random sample of 4,097 Athenian adults. Mean systolic and diastolic blood pressures increased with age in both sexes. Similar findings were observed for mean serum total cholesterol up to age 50 years, but no significant changes were observed in older persons. Smoking was more common for men than for women and less common in those aged more than 50 years. Mean values of body mass index were higher for men than for women in those less than 45 years, but the opposite was observed for the older age groups. The age-adjusted prevalence rate of borderline hypertension was 10.1% for men and 9.1% for women and of stable hypertension (greater than 160/95 mmHg), 8.1% and 8.6%, respectively; the age-adjusted prevalence rate of obesity was 23.5% for men and 23.2% for women and of hypercholesterolemia (total cholesterol greater than or equal to 260 mg/100 ml), 20.1% for men and 17.3% for women. The associations of age and systolic blood pressure and of age and diastolic blood pressure persisted even after controlling for body mass index, total cholesterol, and smoking. In the examined representative sample, the prevalence rates of risk factors for cardiovascular diseases are the same or greater than those in industrialized countries.

摘要

在4097名雅典成年人的随机样本中,研究了希腊此前未调查过的心血管疾病风险因素。男女的平均收缩压和舒张压均随年龄增长而升高。50岁之前,平均血清总胆固醇也有类似的发现,但在老年人中未观察到显著变化。男性吸烟比女性更普遍,50岁以上人群吸烟较少。在45岁以下人群中,男性的体重指数平均值高于女性,但在年龄较大的人群中则相反。年龄调整后的临界高血压患病率男性为10.1%,女性为9.1%;稳定高血压(大于160/95 mmHg)的患病率分别为8.1%和8.6%;肥胖的年龄调整患病率男性为23.5%,女性为23.2%;高胆固醇血症(总胆固醇大于或等于260 mg/100 ml)的患病率男性为20.1%,女性为17.3%。即使在控制了体重指数、总胆固醇和吸烟因素后,年龄与收缩压以及年龄与舒张压之间的关联仍然存在。在所检查的代表性样本中,心血管疾病风险因素的患病率与工业化国家相同或更高。

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