Alavinejad Pezhman, Mousavi Ghanavati Parvin, Alboraie Mohamed, Emara Mohamed, Baghaee Siamak, Baran Bulent, Ebrahimi Daryani Naser, Farsi Farnaz, Hajiani Eskandar, Hashemi Seyed Jalal, Lak Elena, Taheri Yasaman, Dangi Abhijit
Alimentary Tract Research Center, Clinical Sciences Research Institute, Ahvaz Imam Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
World Endoscopy Organization Star Group, Munich, Germany.
Middle East J Dig Dis. 2022 Apr;14(2):222-228. doi: 10.34172/mejdd.2022.276. Epub 2022 Apr 30.
: Irritable bowel syndrome (IBS) is the most frequent functional gastrointestinal (GI) disorder. In this study, we aimed to evaluate the different aspects of IBS among Middle Eastern residents. : During the study period, patients attending gastroenterology clinics of nine tertiary referral centers in four Middle Eastern couturiers (Iran, Egypt, Kuwait, and Turkey) were evaluated by Rome IV diagnostic criteria, and those who fulfilled the diagnostic criteria of IBS were asked to fill in a questionnaire covering different demographics and clinical aspects. : Overall, during a 6-month period, 509 patients with IBS were included. 41.3% of the participants were male (210 patients), and 37.4% of them had academic education. 50% of the participants were Caucasian, and 34% were Arab, and originally, they were citizens of 18 countries. 77.4% of the participants were residents of subtropical areas, while 22.2% were living in temperate regions. The average age of the participants during the first presentation in subtropical and temperate areas were 38.4 ± 12.19 and 38.06 ± 12.18 years, respectively ( = 0.726). The most common subtypes of IBS in subtropical areas were unclassified (IBS-U, 44.4%), constipation dominant (IBS-C, 27.6%), mixed pattern (IBS-M, 21%), and diarrhea dominant (IBS-D, 6.8%) in descending order while in temperate areas the most common subtypes were IBS-U (43.3%), and IBS-D (22.1%), respectively ( < 0.001). Besides abdominal pain, the most common symptom of patients in each region was bloating (62.2% and 68.1%, respectively, = 0.246). The rate of depression and anxiety were significantly higher among the residents of temperate areas in comparison with subtropical regions (41.6% vs. 16.5% and 80.5% vs. 58.4%, respectively, < 0.001). : Although the average age of IBS presentation is the same in subtropical and temperate areas, it seems that in temperate areas, the rate of IBS-D is more prevalent than in subtropical regions. The rate of anxiety and depression are significantly higher among those who searched social media and the internet to get information about their problems.
肠易激综合征（IBS）是最常见的功能性胃肠（GI）疾病。在本研究中，我们旨在评估中东地区居民肠易激综合征的不同方面。：在研究期间，对中东四个国家（伊朗、埃及、科威特和土耳其）九个三级转诊中心胃肠病诊所的患者采用罗马IV诊断标准进行评估，符合肠易激综合征诊断标准的患者被要求填写一份涵盖不同人口统计学和临床方面的问卷。：总体而言，在6个月期间，共纳入509例肠易激综合征患者。41.3%的参与者为男性（210例患者），其中37.4%接受过学术教育。50%的参与者为白种人，34%为阿拉伯人，他们原本是18个国家的公民。77.4%的参与者居住在亚热带地区，而22.2%生活在温带地区。亚热带和温带地区参与者首次就诊时的平均年龄分别为38.4±12.19岁和38.06±12.18岁（P = 0.726）。亚热带地区肠易激综合征最常见的亚型依次为未分类（IBS-U，44.4%）、便秘型（IBS-C，27.6%）、混合型（IBS-M，21%）和腹泻型（IBS-D，6.8%），而在温带地区最常见的亚型分别为IBS-U（43.3%）和IBS-D（22.1%）（P<0.001）。除腹痛外，各地区患者最常见的症状是腹胀（分别为62.2%和68.1%，P = 0.246）。与亚热带地区相比，温带地区居民的抑郁和焦虑发生率显著更高（分别为41.6%对16.5%和80.5%对58.4%，P<0.001）。：尽管亚热带和温带地区肠易激综合征首次就诊的平均年龄相同，但在温带地区，腹泻型肠易激综合征的发生率似乎比亚热带地区更高。在通过社交媒体和互联网搜索自身问题信息的人群中，焦虑和抑郁的发生率显著更高。
