Baumgartner Kathrin, Westerhausen Christoph
Physiology, Institute of Theoretical Medicine, University of Augsburg, 86159 Augsburg, Germany; Hanns-Seidel-Stiftung e.V., 80636 Munich, Germany; Center for NanoScience (CeNS), Ludwig-Maximilians-Universität Munich, 80799 Munich, Germany; Institute of Physics, Experimental Physics I, University of Augsburg, 86159 Augsburg, Germany.
Physiology, Institute of Theoretical Medicine, University of Augsburg, 86159 Augsburg, Germany; Center for NanoScience (CeNS), Ludwig-Maximilians-Universität Munich, 80799 Munich, Germany; Institute of Physics, Experimental Physics I, University of Augsburg, 86159 Augsburg, Germany; Augsburg Center for Innovative Technologies (ACIT), 86159 Augsburg, Germany.
Curr Opin Biotechnol. 2023 Feb;79:102879. doi: 10.1016/j.copbio.2022.102879. Epub 2023 Jan 10.
In the past years, the application of surface acoustic waves (SAWs) as sensors for biological applications has reached high relevance in the field of biotechnology. From rapid advances in designs and materials, new opportunities have emerged, especially for sensing of living cells. Additionally, the combination of SAW sensors with microfluidics and optical microscopy has expanded the market of possible applications. Differentiation of infected and healthy red blood cells or aggressive and nonaggressive tumor cells, and monitoring of wound healing, bacteria, or viral antigen concentrations via SAW-based sensors are only a few examples of recent achievements in cell biology. The rapid growth of this field requires frequent reviewing of the recent progress to maintain high research standards and promote future developments.
在过去几年中，表面声波（SAWs）作为生物应用传感器在生物技术领域已具有高度相关性。随着设计和材料的迅速发展，新的机遇不断涌现，特别是在活细胞传感方面。此外，表面声波传感器与微流体技术和光学显微镜的结合扩大了可能的应用市场。通过基于表面声波的传感器区分受感染和健康的红细胞、侵袭性和非侵袭性肿瘤细胞，以及监测伤口愈合、细菌或病毒抗原浓度，只是细胞生物学近期成果的几个例子。该领域的快速发展需要经常回顾近期进展，以保持高研究标准并促进未来发展。
