Department of Materials Science and Engineering Texas A&M University, College Station, Texas 77843-3003, United States.
Department of Biomedical Engineering, Department of Materials Science and Engineering, Department of Chemistry Texas A&M University, College Station, Texas 77843-3003, United States.
ACS Macro Lett. 2023 Feb 21;12(2):172-182. doi: 10.1021/acsmacrolett.2c00701. Epub 2023 Jan 20.
Silicones have a long history of use in biomedical devices, with unique properties stemming from the siloxane (Si-O-Si) backbone that feature a high degree of flexibility and chemical stability. However, surface, rheological, mechanical, and electrical properties of silicones can limit their utility. Successful modification of silicones to address these limitations could lead to superior and new biomedical devices. Toward improving such properties, recent additive strategies have been leveraged to modify biomedical silicones and are highlighted herein.
硅酮在生物医学设备中有着悠久的应用历史,其独特的性质源于硅氧烷(Si-O-Si)主链,具有高度的柔韧性和化学稳定性。然而,硅酮的表面、流变、机械和电气性能可能会限制其用途。成功地对硅酮进行改性以解决这些限制因素可能会导致更优的新型生物医学设备。为了改善这些性能,最近采用了添加剂策略来改性生物医学硅酮,本文对此进行了重点介绍。