Joo Hyun Seok, Ha Jung-Ki, Hwang Chang Ju, Lee Dong-Ho, Lee Choon Sung, Cho Jae Hwan
Department of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Asian Spine J. 2015 Oct;9(5):798-802. doi: 10.4184/asj.2015.9.5.798. Epub 2015 Sep 22.
Cryptococcus is an encapsulated, yeast-like fungus that rarely causes infection in immunocompetent patients. We present the case report of a 66-year-old female patient with a history of rectal cancer with an isolated lumbar vertebral cryptococcosis proven by biopsy performed during operation. The patient was not an immunocompromised host and did not have any other risk factors except the history of cured rectal cancer. The presumptive diagnosis based on imaging studies was metastatic spine cancer, so operation was performed. However, cryptococcal osteomyelitis was diagnosed in the pathologic examination. This case report emphasizes that we should be aware that lumbar cryptococcosis can be a rare cause of mimicking lesions with metastatic cancer.
隐球菌是一种有荚膜的酵母样真菌,在免疫功能正常的患者中很少引起感染。我们报告一例66岁女性患者,有直肠癌病史,术中活检证实为孤立性腰椎隐球菌病。该患者并非免疫功能低下宿主,除已治愈的直肠癌病史外,没有任何其他危险因素。基于影像学检查的初步诊断为脊柱转移性癌,因此进行了手术。然而,病理检查诊断为隐球菌性骨髓炎。本病例报告强调,我们应意识到腰椎隐球菌病可能是模拟转移性癌病变的罕见原因。