Paul Salomi, Abbas Muhammad S, Nassar Sondos T, Tasha Tasniem, Desai Anjali, Bajgain Anjana, Ali Asna, Dutta Chandrani, Pasha Khadija, Khan Safeera
Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Cureus. 2022 Dec 19;14(12):e32712. doi: 10.7759/cureus.32712. eCollection 2022 Dec.
Gastroesophageal reflux disease (GERD) is a condition characterized by the reflux of stomach contents into the esophagus, which leads to heartburn and regurgitation. GERD has been categorized its types according to severity. The categories that have been discussed in this study are reflux esophagitis (RE), non-erosive reflux disease (NERD), and Barrett's esophagus. Our study compared various studies and showed that the subjects with GERD had a high level of anxiety and depression. Gastroesophageal reflux disease has a significant negative impact on the quality of life (QoL) by perturbing daily activities. The majority of GERD patients use antacid drugs to control their acid symptoms. However, these symptoms are sometimes difficult to control, even with the most potent proton-pump inhibitors (PPIs), and these patients tend to have a lower response rate. According to the clinical data, Anxiety and Depression are linked to the development of GERD. A major focus of this study is to explore psychological influences such as anxiety and depression and how they relate to GERD. This study also reviews the effect of these conditions on the younger population. It is concluded that the quality of life (QoL) of subjects with GERD is reduced by depression and anxiety.
胃食管反流病(GERD)是一种以胃内容物反流至食管为特征的疾病,可导致烧心和反流。GERD已根据严重程度进行了分类。本研究中讨论的类别包括反流性食管炎(RE)、非糜烂性反流病(NERD)和巴雷特食管。我们的研究比较了各种研究,结果显示GERD患者存在高度焦虑和抑郁情绪。胃食管反流病通过干扰日常活动对生活质量(QoL)产生重大负面影响。大多数GERD患者使用抗酸药物来控制胃酸症状。然而,即使使用最有效的质子泵抑制剂(PPI),这些症状有时也难以控制,而且这些患者的反应率往往较低。根据临床数据,焦虑和抑郁与GERD的发生有关。本研究的一个主要重点是探讨焦虑和抑郁等心理影响因素以及它们与GERD的关系。本研究还回顾了这些情况对年轻人群的影响。研究得出结论,抑郁和焦虑会降低GERD患者的生活质量(QoL)。