Patterson Rob, Rogiewicz Anna, Kiarie Elijah G, Slominski Bogdan A
CBS BioPlatforms Inc., Calgary, AB, Canada.
Department of Animal Science, University of Manitoba, Winnipeg, MB, Canada.
Front Vet Sci. 2023 Jan 6;9:1067383. doi: 10.3389/fvets.2022.1067383. eCollection 2022.
With a long history of inclusion within livestock feeding programs, yeast and their respective derivatives are well-understood from a nutritional perspective. Originally used as sources of highly digestible protein in young animal rations in order to offset the use of conventional protein sources such as soybean and fish meal, application strategies have expanded in recent years into non-nutritional uses for all animal categories. For the case of yeast derivatives, product streams coming from the downstream processing of nutritional yeast, the expansion in use cases across species groups has been driven by a greater understanding of the composition of each derivative along with deeper knowledge of mechanistic action of key functional components. From improving feed efficiency, to serving as alternatives to antibiotic growth promoters and supporting intestinal health and immunity while mitigating pathogen shedding, new use cases are driven by a recognition that yeast derivatives contain specific bioactive compounds that possess functional properties. This review will attempt to highlight key bioactive categories within industrially applicable yeast derivatives and provide context regarding identification and characterization and mechanisms of action related to efficacy within a range of experimental models.
酵母及其衍生物长期被纳入家畜饲养计划，从营养角度来看已被充分了解。酵母最初被用作幼畜日粮中高消化率蛋白质的来源，以替代大豆和鱼粉等传统蛋白质来源，近年来其应用策略已扩展到所有动物类别的非营养用途。就酵母衍生物而言，它们是营养酵母下游加工产生的产品流，跨物种群体用例的扩展是由于对每种衍生物的成分有了更深入的了解，以及对关键功能成分作用机制有了更深入的认识。从提高饲料效率，到作为抗生素生长促进剂的替代品，以及支持肠道健康和免疫力同时减少病原体排放，新的用例是基于认识到酵母衍生物含有具有功能特性的特定生物活性化合物。本综述将试图突出工业适用酵母衍生物中的关键生物活性类别，并提供有关在一系列实验模型中与功效相关的鉴定、表征和作用机制的背景信息。
