Primary Care and Population Health, University College London, London, UK
Institute of Sport, Exercise and Health, University College London, London, UK.
J Epidemiol Community Health. 2023 Mar;77(3):189-195. doi: 10.1136/jech-2022-219829. Epub 2023 Jan 23.
Movement behaviours (eg, sedentary behaviour (SB), moderate and vigorous physical activity (MVPA), light intensity physical activity (LIPA) and sleep) are linked to cognition, yet the relative importance of each component is unclear, and not yet explored with compositional methodologies.
To (i) assess the associations of different components of daily movement and participant's overall cognition, memory and executive function, and (ii) understand the relative importance of each individual component for cognition.
The 1970 British Cohort Study (BCS70) is a prospective birth cohort study of UK-born adults. At age 46, participants consented to wear an accelerometer device and complete tests of verbal memory and executive function. Compositional linear regression was used to examine cross-sectional associations between 24-hour movement behaviours and standardised cognition scores. Isotemporal substitution was performed to model the effect of reallocating time between components of daily movement on cognition.
The sample comprised 4481 participants (52% female). Time in MVPA relative to SB, LIPA and sleep was positively associated with cognition after adjustments for education and occupational physical activity, but additional adjustment for health status attenuated associations. SB relative to all other movements was robustly positively associated with cognition. Modelling time reallocation between components revealed an increase in cognition centile after MVPA theoretically replaced 9 min of SB (OR=1.31; 95% CI 0.09 to 2.50), 7 min of LIPA (1.27; 0.07 to 2.46) or 7 min of sleep (1.20; 0.01 to 2.39).
Relative to time spent in other behaviours, greater MVPA and SB was associated with higher cognitive scores. Loss of MVPA time, given its smaller relative amount, appears most deleterious. Efforts should be made to preserve MVPA time, or reinforce it in place of other behaviours.
运动行为（如久坐行为（SB）、中高强度体力活动（MVPA）、低强度体力活动（LIPA）和睡眠）与认知有关，但每个组成部分的相对重要性尚不清楚，并且尚未用组成方法学进行探索。
（i）评估日常运动的不同组成部分与参与者整体认知、记忆和执行功能的关联，以及（ii）了解每个单独组成部分对认知的相对重要性。
1970 年英国队列研究（BCS70）是一项针对英国出生成年人的前瞻性出生队列研究。在 46 岁时，参与者同意佩戴加速度计设备并完成言语记忆和执行功能测试。组成线性回归用于检查 24 小时运动行为与标准化认知评分之间的横断面关联。等时替代法用于模拟在日常运动的各个组成部分之间重新分配时间对认知的影响。
样本包括 4481 名参与者（52%为女性）。在调整教育和职业体力活动后，MVPA 相对于 SB、LIPA 和睡眠的时间与认知呈正相关，但进一步调整健康状况会减弱关联。SB 相对于所有其他运动与认知呈稳健正相关。对成分之间的时间再分配进行建模后，MVPA 在理论上取代 9 分钟 SB（OR=1.31；95%CI 0.09 至 2.50）、7 分钟 LIPA（1.27；0.07 至 2.46）或 7 分钟睡眠（1.20；0.01 至 2.39）后，认知百分位数增加。
与其他行为相比，MVPA 和 SB 时间的增加与较高的认知评分相关。鉴于 MVPA 时间相对较少，失去 MVPA 时间的影响似乎最为有害。应努力保持 MVPA 时间，或用其代替其他行为进行强化。
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