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新冠疫情风险缓解行为与青少年特定精神障碍之间的关联。

Association between COVID-19 risk-mitigation behaviors and specific mental disorders in youth.

作者信息

Conway Kevin P, Bhardwaj Kriti, Michel Emmanuella, Paksarian Diana, Nikolaidis Aki, Kang Minji, Merikangas Kathleen R, Milham Michael P

机构信息

Genetic Epidemiology Research Branch, National Institute of Mental Health, 35 Convent Drive, Building 35A, Bethesda, MD, 20892-3720, USA.

Center for the Developing Brain, The Child Mind Institute, New York, NY, USA.

出版信息

Child Adolesc Psychiatry Ment Health. 2023 Jan 24;17(1):14. doi: 10.1186/s13034-023-00561-7.

Abstract

BACKGROUND

Although studies of adults show that pre-existing mental disorders increase risk for COVID-19 infection and severity, there is limited information about this association among youth. Mental disorders in general as well as specific types of disorders may influence the ability to comply with risk-mitigation strategies to reduce COVID-19 infection and transmission.

METHODS

Youth compliance (rated as "Never," "Sometimes," "Often," or "Very often/Always") with risk mitigation was reported by parents on the CoRonavIruS Health Impact Survey (CRISIS) in January 2021. The sample comprised 314 female and 514 male participants from the large-scale Child Mind Institute Healthy Brain Network, a transdiagnostic self-referred, community sample of children and adolescents (ages 5-21). Responses were summarized using factor analysis of risk mitigation, and their associations with lifetime mental disorders (assessed via structured diagnostic interviews) were identified with linear regression analyses (adjusted for covariates). All analyses used R Project for Statistical Computing for Mac (v.4.0.5).

RESULTS

A two-factor model was the best-fitting solution. Factor 1 (avoidance behaviors) included avoiding groups, indoor settings, and other peoples' homes; avoidance scores were higher among youth with any anxiety disorder (p = .01). Factor 2 (hygiene behaviors) included using hand sanitizer, washing hands, and maintaining social distance; hygiene scores were lower among youth with ADHD (combined type) (p = .02). Mask wearing was common (90%), did not load on either factor, and was not associated with any mental health disorder.

CONCLUSION AND RELEVANCE

Although most mental disorders examined were not associated with risk mitigation, youth with ADHD characterized by hyperactivity plus inattention may need additional support to consistently engage in risk-mitigation behaviors. Enhancing risk-mitigation strategies among at-risk groups of youth may help reduce COVID-19 infection and transmission.

摘要

背景

尽管针对成年人的研究表明,既往存在的精神障碍会增加感染新冠病毒以及感染后病情严重程度的风险,但关于青少年中这一关联的信息有限。一般的精神障碍以及特定类型的精神障碍可能会影响遵守降低新冠病毒感染和传播风险策略的能力。

方法

家长于2021年1月在新冠病毒健康影响调查(CRISIS)中报告了青少年遵守降低风险措施的情况(分为“从不”“有时”“经常”或“非常经常/总是”)。样本包括来自大规模儿童心理研究所健康大脑网络的314名女性和514名男性参与者,这是一个自我推荐的跨诊断社区样本,涵盖儿童和青少年(5至21岁)。通过对降低风险措施进行因子分析来总结回答情况,并通过线性回归分析(对协变量进行调整)确定其与终生精神障碍(通过结构化诊断访谈评估)之间的关联。所有分析均使用适用于Mac的R统计计算项目(版本4.0.5)。

结果

双因素模型是最佳拟合方案。因素1(回避行为)包括避免参加群体活动、待在室内以及前往他人家中;在患有任何焦虑症的青少年中,回避得分更高(p = 0.01)。因素2(卫生行为)包括使用洗手液、洗手和保持社交距离;患有注意缺陷多动障碍(合并型)的青少年的卫生得分较低(p = 0.02)。佩戴口罩很普遍(90%),不属于任何一个因素,且与任何心理健康障碍均无关联。

结论及意义

尽管所研究的大多数精神障碍与降低风险措施无关,但以多动和注意力不集中为特征的注意缺陷多动障碍青少年可能需要额外支持,以持续采取降低风险行为。加强高危青少年群体的降低风险策略可能有助于减少新冠病毒的感染和传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bff/9875423/eb8c51757c44/13034_2023_561_Fig1_HTML.jpg

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