Department of Medical Mycology, Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands.
Institute for Biodiversity and Ecosystem Dynamics (IBED), University of Amsterdam, Amsterdam, The Netherlands.
Med Mycol. 2023 Feb 3;61(2). doi: 10.1093/mmy/myad009.
Invasive fungal infections caused by non-albicans Candida species are increasingly reported. Recent advances in diagnostic and molecular tools enabled better identification and detection of emerging pathogenic yeasts. The Candida haemulonii species complex accommodates several rare and recently described pathogenic species, C. duobushaemulonii, C. pseudohaemulonii, C. vulturna, and the most notorious example is the outbreak-causing multi-drug resistant member C. auris. Here, we describe a new clinically relevant yeast isolated from geographically distinct regions, representing the proposed novel species C. khanbhai, a member of the C. haemulonii species complex. Moreover, several members of the C. haemulonii species complex were observed to be invalidly described, including the clinically relevant species C. auris and C. vulturna. Hence, the opportunity was taken to correct this here, formally validating the names of C. auris, C. chanthaburiensis, C. konsanensis, C. metrosideri, C. ohialehuae, and C. vulturna.
非白念珠菌属念珠菌引起的侵袭性真菌感染的报道越来越多。最近诊断和分子工具的进步使新兴致病性酵母的鉴定和检测变得更好。半滑念珠菌种复合体容纳了几种罕见和最近描述的致病性物种，包括双头半滑念珠菌、拟热带念珠菌、沃氏假丝酵母，最臭名昭著的例子是引起爆发的多药耐药成员耳念珠菌。在这里，我们描述了一种从地理位置不同的地区分离出来的新的临床相关酵母，代表了拟议的新型物种 C. khanbhai，它是半滑念珠菌种复合体的成员。此外，还观察到半滑念珠菌种复合体的几个成员被无效描述，包括临床相关的物种耳念珠菌和沃氏假丝酵母。因此，有机会在这里纠正这一点，正式确认耳念珠菌、康氏假丝酵母、广口假丝酵母、滨海假丝酵母、奥利亚假丝酵母和沃氏假丝酵母的名称。
