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血球念珠酵母复合种的扩展——从临床和环境来源分离出的新物种莫氏念珠酵母

Expansion of the Candidozyma haemuli Species Complex - The Novel Species Candidozyma molenica, Isolated from Clinical and Environmental Sources.

作者信息

Zandijk Annemarie, van der Bruggen Tjomme, Sipiczki Matthias, Tissing Wim J E, Wolfs Tom F W, Gerrits van den Ende Bert, Groenewald Marizeth, Hagen Ferry

机构信息

Department of Medical Mycology, Westerdijk Fungal Biodiversity Institute (WI-KNAW), Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

Mycopathologia. 2025 Sep 1;190(5):81. doi: 10.1007/s11046-025-00985-z.

Abstract

Due to the recent unprecedented global rise of Candidozyma auris in hospital environments the members of the Candidozyma haemuli species complex have raised significant interest of clinicians and researchers. Until the finding of C. auris, the species complex did not receive much attention as the known pathogenic species were only rarely encountered in hospitals and clinical diagnostic laboratories. During the past years several new species were described, such as Candidozyma khanbhai and Candidozyma vulturna, that were found to be of clinical importance. Here, we used phylogenetic and phenotypic analyses -including antifungal susceptibility testing- to characterize and describe a new and potentially clinically relevant yeast that we obtained from clinical specimen and flowers, representing the proposed novel species Candidozyma molenica.

摘要

由于近期医院环境中奥里假丝酵母在全球范围内前所未有的增加,血耳假丝酵母物种复合体成员引起了临床医生和研究人员的极大兴趣。在发现奥里假丝酵母之前,该物种复合体并未受到太多关注,因为已知的致病物种在医院和临床诊断实验室中很少遇到。在过去几年中,描述了几个新物种,如坎氏假丝酵母和秃鹫假丝酵母,发现它们具有临床重要性。在这里,我们使用系统发育和表型分析——包括抗真菌药敏试验——来表征和描述一种从临床标本和花朵中获得的新的、可能具有临床相关性的酵母,它代表了拟议的新物种莫氏假丝酵母。

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