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芦丁生物合成途径及治疗潜力概述。

An Overview of Biosynthetic Pathway and Therapeutic Potential of Rutin.

机构信息

Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana, 124001, India.

出版信息

Mini Rev Med Chem. 2023;23(14):1451-1460. doi: 10.2174/1389557523666230125104101.

DOI:10.2174/1389557523666230125104101
PMID:36698235
Abstract

Flavonoids are compounds abundantly found in nature and known as a polyphenolic group of compounds having flavancore and show the utmost abundant collection of complexes and are found in fiber-rich root vegetables, fruits, and their eatable items. Due to the presence of hydroxyl groups, flavonoids show various therapeutic activities like antioxidant, antibacterial, antiviral, and antiinflammatory. Substituent groups are responsible for the onset of biochemical actions of flavonoids, which affect the metabolism. The major example of flavonol is rutin, which is constituted of rutinose and quercetin. It is a glycosidic type of flavonoid, similarly identified as purple quercitrin and Vitamin P with over 70 plant species and plant-derived foods, exclusively grapefruit, buckwheat seeds, cherries, apricots, grapes, onions, plums, and oranges. Another name forrutin is a citrus flavonoid known as rutoside, and sophorin. Rutin is a polyphenolic compound having a low molecular weight.

摘要

类黄酮是在自然界中大量存在的化合物,被称为多酚类化合物,具有黄酮核,显示出最丰富的复合物集合,并存在于富含纤维的根菜类、水果及其可食用物品中。由于存在羟基,类黄酮表现出各种治疗活性,如抗氧化、抗菌、抗病毒和抗炎。取代基负责类黄酮生化作用的开始,这会影响新陈代谢。黄酮醇的主要例子是芦丁,它由芦丁糖和槲皮素组成。它是一种糖苷型类黄酮,同样被鉴定为紫色槲皮苷和维生素 P,存在于 70 多种植物物种和植物源性食品中,仅在葡萄柚、荞麦种子、樱桃、杏、葡萄、洋葱、李子和橙子中发现。芦丁的另一个名称是柑橘类黄酮,称为芦丁苷和槐糖苷。芦丁是一种具有低分子量的多酚化合物。

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