European Environment Agency (EEA), Kongens Nytorv 6, 1050 Copenhagen K, Denmark.
European Environment Agency (EEA), Kongens Nytorv 6, 1050 Copenhagen K, Denmark.
Int J Hyg Environ Health. 2023 Mar;248:114111. doi: 10.1016/j.ijheh.2023.114111. Epub 2023 Jan 25.
One of the major goals of the European Human Biomonitoring Initiative (HBM4EU) was to bridge the gap between science and policy by consulting both policy makers and national scientists and generating evidence of the actual exposure of residents to chemicals and whether that exposure would be suggest a potential health risk. Residents' perspectives on chemical exposure and risk were also investigated. HBM4EU's research was designed to answer specific short-term and long-term policy questions at national and European levels, and for its results to directly support regulatory action on chemicals. A strategy was established to prioritise chemicals for analysis in human matrices, with a total of 18 substances/substance groups chosen to be investigated throughout the five-and a -half-year project. HBM4EU produced new evidence of human exposure levels, developed reference values for exposure, investigated determinants of exposure and derived health-based guidance values for those substances. In addition, HBM4EU promoted the use of human biomonitoring data in chemical risk assessment and developed innovative tools and methods linking chemicals to possible health impacts, such as effect biomarkers. Furthermore, HBM4EU advanced understand of effects from combined exposures and methods to identify emerging chemicals. With the aim of supporting policy implementation, science-to-policy workshops were organised, providing opportunities for joint reflection and dialogue on research results. I, and indicators were developed to assess temporal and spatial patterns in the exposure of European population. A sustainable human biomonitoring monitoring framework, producing comparable quality assured data would allow: the evaluation of time trends; the exploration of spatial trends: the evaluation of the influence of socio-economic conditions on chemical exposure. Therefore, such a framework should be included in the European Chemicals' Strategy for Sustainability and the data would support the Zero Pollution Action Plan.
欧洲人类生物监测倡议 (HBM4EU) 的主要目标之一是通过咨询政策制定者和国家科学家,弥合科学与政策之间的差距,并生成居民实际接触化学物质的证据,以及这种接触是否会带来潜在的健康风险。还调查了居民对化学物质暴露和风险的看法。HBM4EU 的研究旨在回答国家和欧洲层面的具体短期和长期政策问题,并为其结果直接支持对化学物质的监管行动。制定了一项战略,优先考虑在人体基质中分析化学物质,在整个五年半的项目中总共选择了 18 种物质/物质组进行调查。HBM4EU 提供了人类接触水平的新证据,为接触制定了参考值,调查了接触的决定因素,并为这些物质制定了基于健康的指导值。此外,HBM4EU 促进了人类生物监测数据在化学风险评估中的使用,并开发了将化学物质与可能的健康影响(如效应生物标志物)联系起来的创新工具和方法。此外,HBM4EU 增进了对联合暴露的影响的理解,并开发了识别新兴化学物质的方法。为了支持政策实施,组织了科学政策研讨会,为共同反思和讨论研究结果提供了机会。我,并制定了指标来评估欧洲人口暴露的时间和空间模式。可持续的人类生物监测监测框架,产生具有可比质量保证的数据将允许:评估时间趋势;探索空间趋势:评估社会经济条件对化学物质暴露的影响。因此,这样的框架应该包含在欧洲化学品可持续性战略中,并且数据将支持零污染行动计划。