Hernández-Montes V, Buitrago-Sierra R, Echeverry-Rendón Mónica, Santa-Marín J F
Universidad Nacional de Colombia. Sede Medellín. Facultad de Minas. Medellín, Colombia, Grupo de Tribología y Superficies Medellín Colombia
Instituto Tecnológico Metropolitano (ITM). Facultad de Ingenierías, Grupo de Materiales Avanzados y Energía (MATyER) Medellín Colombia.
RSC Adv. 2023 Jan 9;13(2):1422-1433. doi: 10.1039/d2ra06312c. eCollection 2023 Jan 3.
Magnesium alloys are being studied for use in temporary orthopedic implants because of their mechanical properties, which are similar to those of human bone, and their good biocompatibility. However, their application is limited due to their rapid degradation, and early loss of their mechanical properties, decreasing the stability of the implant and its proper synchronization with tissue regeneration. In this regard, various surface coatings have been used to improve their biological, physico-chemical and biodegradation properties. Currently, one of the most explored strategies is using smart coatings because of their self-healing properties that can slow down the corrosion process of Mg and its alloys. Ceria-based materials show promise as coatings for these alloys. Their unique redox capacity not only provides Mg alloys with good self-healing properties but also interesting biological properties, which are described in this paper. Despite this, some problems and challenges related to the biocompatibility and application of these materials in coatings remain unsolved. In this article, a critical review is presented summarizing the most representative literature on ceria-based coatings on Mg alloys for their potential use as biomaterials. The results show that ceria is a versatile material that may be used in industrial and biomedical applications.
镁合金因其机械性能与人体骨骼相似且具有良好的生物相容性,正被研究用于临时骨科植入物。然而,由于其快速降解以及机械性能的早期丧失,降低了植入物的稳定性及其与组织再生的适当同步性,其应用受到限制。在这方面,各种表面涂层已被用于改善其生物学、物理化学和生物降解性能。目前,最受探索的策略之一是使用智能涂层,因为它们具有自修复性能,可以减缓镁及其合金的腐蚀过程。基于氧化铈的材料有望作为这些合金的涂层。它们独特的氧化还原能力不仅赋予镁合金良好的自修复性能,还具有有趣的生物学特性,本文将对此进行描述。尽管如此,与这些材料在涂层中的生物相容性和应用相关的一些问题和挑战仍未解决。本文进行了批判性综述,总结了关于镁合金上基于氧化铈涂层作为生物材料潜在用途的最具代表性的文献。结果表明,氧化铈是一种多功能材料,可用于工业和生物医学应用。