Ahmad Suhail, Asadzadeh Mohammad
Faculty of Medicine, Department of Microbiology, Kuwait University, PO Box: 24923, 13110 Safat, Kuwait.
Curr Fungal Infect Rep. 2023;17(1):36-48. doi: 10.1007/s12281-023-00451-7. Epub 2023 Jan 26.
, a recently recognized yeast pathogen, has become a major public health threat due to the problems associated with its accurate identification, intrinsic and acquired resistance to antifungal drugs, and its potential to easily contaminate the environment causing clonal outbreaks in healthcare facilities. These outbreaks are associated with high mortality rates particularly among older patients with multiple comorbidities under intensive care settings. The purpose of this review is to highlight strategies that are being adapted to prevent transmission of in healthcare settings.
Colonized patients shed into their environment which contaminates surrounding equipment. It resists elimination even by robust decontamination procedures and is easily transmitted to new patients during close contact resulting in outbreaks. Efforts are being made to rapidly identify -infected/-colonized patients, to determine its susceptibility to antifungals, and to perform effective cleaning and decontamination of the environment and isolation of colonized patients to prevent further transmission.
Rapid and accurate identification of hospitalized patients infected/colonized with , rapid detection of its susceptibility patterns, and appropriate use of infection control measures can help to contain the spread of this highly pathogenic yeast in healthcare settings and prevent/control outbreaks.
是一种最近才被认识的酵母病原体,由于其准确鉴定存在问题、对抗真菌药物具有固有和获得性耐药性,以及易于污染环境导致医疗机构内克隆性暴发,已成为重大的公共卫生威胁。这些暴发与高死亡率相关,尤其是在重症监护环境下患有多种合并症的老年患者中。本综述的目的是强调为预防 在医疗机构内传播而正在采用的策略。
定植患者将 排放到其环境中,从而污染周围设备。即使通过强有力的去污程序,它也难以消除,并且在密切接触期间很容易传播给新患者,导致暴发。目前正在努力快速识别感染/定植 的患者,确定其对抗真菌药物的敏感性,并对环境进行有效的清洁和去污以及对定植患者进行隔离,以防止进一步传播。
快速准确地识别住院的感染/定植 的患者,快速检测其药敏模式,并适当使用感染控制措施,有助于遏制这种高致病性酵母在医疗机构内的传播,并预防/控制暴发。