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一例伴有CRTC1::TRIM11融合的指部皮肤黑素细胞肿瘤

A Case of Digital Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Fusion.

作者信息

Bui Chau M, Chaum Manita, Balzer Bonnie

机构信息

Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, USA.

出版信息

Cureus. 2022 Dec 31;14(12):e33179. doi: 10.7759/cureus.33179. eCollection 2022 Dec.

Abstract

A cutaneous melanocytic tumor with fusion (CMTCT) was recently described as a novel superficial tumor with melanocytic differentiation and harboring a unique in-frame translocation, . This emerging entity can occur at any age and is known to be a low-grade malignant neoplasm with limited follow-up data. There are no available guidelines for the management and treatment of this tumor. This neoplasm has been found in the extremities, head and neck, and trunk. Here, we present the first case occurring on acral digital skin. This case contributes to the growing knowledge surrounding this newly described entity.

摘要

一种具有融合特征的皮肤黑素细胞肿瘤(CMTCT)最近被描述为一种具有黑素细胞分化的新型浅表肿瘤,伴有独特的框内易位。这种新出现的实体可发生于任何年龄,已知是一种低级别恶性肿瘤,随访数据有限。目前尚无针对该肿瘤管理和治疗的可用指南。这种肿瘤已在四肢、头颈部和躯干中发现。在此,我们报告首例发生于指端皮肤的病例。该病例有助于增加围绕这个新描述实体的知识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a22d/9886156/336cecc1e210/cureus-0014-00000033179-i01.jpg

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